| Game Date | Conference | Road Team | Score | Home Team | Score | Box Score | Recap | Commentary | |
|---|---|---|---|---|---|---|---|---|---|
| 2/10/2006 | Northwestern | 2 | at | South Florida | 5 | Box Score | Recap | ||
| 2/11/2006 | Northwestern | 2 | at | South Florida | 0 | Box Score | Recap | 13 innings | |
| 2/12/2006 | Northwestern | 8 | at | South Florida | 9 | Box Score | Recap | ||
| 2/17/2006 | Northwestern | 3 | at | Virginia Commonwealth | 4 | Box Score | Recap | ||
| 2/17/2006 | Penn State | 4 | at | Tulane | 9 | Box Score | Recap | ||
| 2/18/2006 | Northwestern | 6 | at | Virginia Commonwealth | 5 | Box Score | Recap | 10 innings | |
| 2/18/2006 | Penn State | 0 | at | Tulane | 12 | Box Score | Recap | ||
| 2/19/2006 | Northwestern | at | Virginia Commonwealth | Recap | CCD, cold | ||||
| 2/19/2006 | Penn State | 3 | at | Tulane | 9 | Box Score | Recap | ||
| 2/24/2006 | Alabama-Birmingham | 5 | vs | Michigan | 4 | Box Score | Recap | Wiregrass Classic, Dothan, AL | |
| 2/24/2006 | Illinois | 3 | at | Stetson | 6 | Box Score | Recap | Stetson Invitational, DeLand, FL | |
| 2/24/2006 | Indiana | 3 | at | North Carolina-Charlotte | 11 | Box Score | Recap | ||
| 2/24/2006 | Iowa | 12 | at | Austin Peay State | 10 | Box Score | Recap | Austin Peay Invitational, Clarksville, TN | |
| 2/24/2006 | Michigan State | 1 | at | Lamar | 8 | Box Score | Recap | Cardinal Classic, Beaumont, TX | |
| 2/24/2006 | Minnesota | 0 | at | Florida State | 5 | Box Score | Recap | ||
| 2/24/2006 | Northwestern | 0 | at | Louisville | 11 | Box Score | Recap | ||
| 2/24/2006 | Northwestern | 5 | at | Louisville | 4 | Box Score | Recap | ||
| 2/24/2006 | Ohio State | 2 | vs | Wake Forest | 6 | Box Score | Recap | The Pepsi Baseball Classic, Gainesville, FL | |
| 2/24/2006 | Penn State | 3 | at | East Carolina | 4 | Box Score | Recap | Keith LeClair Classic, Greenville, NC | |
| 2/24/2006 | Purdue | 5 | at | Louisiana-Lafayette | 1 | Box Score | Recap | Mardi Gras Ball Tournament, Lafayette, LA | |
| 2/25/2006 | Illinois State | 0 | vs | Iowa | 10 | Box Score | Recap | Austin Peay Invitational, Clarksville, TN | |
| 2/25/2006 | Indiana | 1 | at | North Carolina-Charlotte | 7 | Box Score | Recap | ||
| 2/25/2006 | Louisiana-Monroe | vs | Purdue | Recap | CCD, rain (Mardi Gras Ball Tournament, Lafayette, LA) | ||||
| 2/25/2006 | Michigan | vs | Troy | Recap | PPD to 2/26, rain (Wiregrass Classic, Dothan, AL) | ||||
| 2/25/2006 | Michigan State | 8 | vs | Arkansas State | 9 | Box Score | Recap | Cardinal Classic, Beaumont, TX | |
| 2/25/2006 | Michigan State | at | Lamar | Recap | CCD, rain (Cardinal Classic, Beaumont, TX) | ||||
| 2/25/2006 | Minnesota | 4 | at | Florida State | 12 | Box Score | Recap | 1,400th win for Mike Martin | |
| 2/25/2006 | North Carolina State | 3 | vs | Penn State | 2 | Box Score | Recap | Keith LeClair Classic, Greenville, NC | |
| 2/25/2006 | Northwestern | 7 | at | Louisville | 8 | Box Score | Recap | 11 innings | |
| 2/25/2006 | Ohio State | 3 | at | Florida | 10 | Box Score | Recap | The Pepsi Baseball Classic, Gainesville, FL | |
| 2/25/2006 | South Florida | 4 | vs | Illinois | 2 | Box Score | Recap | Stetson Invitational, DeLand, FL | |
| 2/26/2006 | Illinois | 13 | vs | Western Carolina | 14 | Box Score | Recap | Stetson Invitational, DeLand, FL | |
| 2/26/2006 | Indiana | 10 | at | North Carolina-Charlotte | 11 | Box Score | Recap | 14 innings | |
| 2/26/2006 | Iowa | 6 | vs | Dayton | 3 | Box Score | Recap | Austin Peay Invitational, Clarksville, TN | |
| 2/26/2006 | Kansas State | 9 | vs | Purdue | 3 | Box Score | Recap | Mardi Gras Ball Tournament, Lafayette, LA | |
| 2/26/2006 | Kentucky | 9 | vs | Michigan State | 2 | Box Score | Recap | Cardinal Classic, Beaumont, TX | |
| 2/26/2006 | Michigan | 4 | vs | South Alabama | 9 | Box Score | Recap | Wiregrass Classic, Dothan, AL | |
| 2/26/2006 | Michigan | 7 | vs | Troy | 5 | Box Score | Recap | makeup of 2/25 game (Wiregrass Classic, Dothan, AL) | |
| 2/26/2006 | Minnesota | 6 | at | Florida State | 8 | Box Score | Recap | ||
| 2/26/2006 | Missouri | 2 | vs | Ohio State | 4 | Box Score | Recap | The Pepsi Baseball Classic, Gainesville, FL | |
| 2/26/2006 | Penn State | 4 | vs | West Virginia | 5 | Box Score | Recap | Keith LeClair Classic, Greenville, NC (10 innings) | |
| 3/1/2006 | Michigan | 6 | at | UCF | 3 | Box Score | Recap | ||
| 3/3/2006 | Arizona | 7 | at | Minnesota | 2 | Box Score | Recap | Dairy Queen Classic, Minneapolis, MN | |
| 3/3/2006 | Illinois | 5 | at | South Florida | 1 | Box Score | Recap | ||
| 3/3/2006 | Indiana | 0 | at | Miami, Florida | 4 | Box Score | Recap | ||
| 3/3/2006 | Iowa | 2 | vs | Northwestern State | 0 | Box Score | Recap | Louisiana-Lafayette Invitational, Lafayette, LA | |
| 3/3/2006 | Michigan | 6 | vs | North Carolina-Asheville | 8 | Box Score | Recap | Georgia Southern Invitational, Statesboro, GA | |
| 3/3/2006 | Northwestern | 3 | at | Kentucky | 19 | Box Score | Recap | ||
| 3/3/2006 | Ohio State | 12 | vs | North Carolina-Greensboro | 2 | Box Score | Recap | Kennel Club Classic, Jacksonville, FL | |
| 3/3/2006 | Purdue | 5 | at | North Carolina | 4 | Box Score | Recap | ||
| 3/4/2006 | Illinois | 7 | at | South Florida | 3 | Box Score | Recap | ||
| 3/4/2006 | Indiana | 2 | at | Miami, Florida | 7 | Box Score | Recap | ||
| 3/4/2006 | Iowa | 9 | at | Louisiana-Lafayette | 14 | Box Score | Recap | Louisiana-Lafayette Invitational, Lafayette, LA | |
| 3/4/2006 | Lehigh | 3 | vs | Michigan State | 6 | Box Score | Recap | Clearwater, FL | |
| 3/4/2006 | Michigan | 3 | at | Georgia Southern | 4 | Box Score | Recap | Georgia Southern Invitational, Statesboro, GA (10 innings) | |
| 3/4/2006 | Northwestern | 7 | at | Kentucky | 12 | Box Score | Recap | ||
| 3/4/2006 | Notre Dame | 0 | at | Minnesota | 8 | Box Score | Recap | Dairy Queen Classic, Minneapolis, MN | |
| 3/4/2006 | Ohio State | 3 | at | Jacksonville | 4 | Box Score | Recap | Kennel Club Classic, Jacksonville, FL | |
| 3/4/2006 | Penn State | 4 | vs | Bowling Green State | 5 | Box Score | Recap | Bradenton, FL | |
| 3/4/2006 | Purdue | 2 | at | North Carolina | 5 | Box Score | Recap | ||
| 3/5/2006 | Evansville | 4 | vs | Iowa | 6 | Box Score | Recap | Louisiana-Lafayette Invitational, Lafayette, LA | |
| 3/5/2006 | Illinois | 7 | at | South Florida | 6 | Box Score | Recap | ||
| 3/5/2006 | Indiana | 4 | at | Miami, Florida | 6 | Box Score | Recap | ||
| 3/5/2006 | LeMoyne | 4 | vs | Michigan | 9 | Box Score | Recap | Georgia Southern Invitational, Statesboro, GA | |
| 3/5/2006 | Nebraska | 4 | at | Minnesota | 1 | Box Score | Recap | Dairy Queen Classic, Minneapolis, MN | |
| 3/5/2006 | Northwestern | 3 | at | Kentucky | 10 | Box Score | Recap | ||
| 3/5/2006 | Penn State | 17 | vs | Sacred Heart | 2 | Box Score | Recap | Clearwater, FL | |
| 3/5/2006 | Purdue | 3 | at | North Carolina | 7 | Box Score | Recap | ||
| 3/5/2006 | Sacred Heart | 2 | vs | Michigan State | 8 | Box Score | Recap | Clearwater, FL | |
| 3/5/2006 | Western Michigan | 12 | vs | Ohio State | 11 | Box Score | Recap | Kennel Club Classic, Jacksonville, FL | |
| 3/6/2006 | Central Michigan | 3 | vs | Penn State | 1 | Box Score | Recap | Clearwater, FL | |
| 3/6/2006 | Michigan State | 15 | vs | Lehigh | 6 | Box Score | Recap | Clearwater, FL | |
| 3/7/2006 | Indiana | 7 | at | Indiana State | 4 | Box Score | Recap | ||
| 3/7/2006 | Lehigh | 0 | vs | Penn State | 4 | Box Score | Recap | Clearwater, FL | |
| 3/7/2006 | Michigan State | 2 | at | Florida International | 3 | Box Score | Recap | 10 innings | |
| 3/8/2006 | Jacksonville | 7 | vs | Penn State | 3 | Box Score | Recap | Clearwater, FL | |
| 3/8/2006 | Michigan State | 4 | at | Miami, Florida | 9 | Box Score | Recap | ||
| 3/8/2006 | North Dakota State | 4 | at | Minnesota | 5 | Box Score | Recap | ||
| 3/8/2006 | Xavier | at | Indiana | Recap | PPD to 4/26, rain | ||||
| 3/9/2006 | Seton Hall | 3 | vs | Michigan State | 4 | Box Score | Recap | Boca Raton, FL (10 innings) | |
| 3/10/2006 | Bethune-Cookman | 5 | vs | Penn State | 6 | Box Score | Recap | Clearwater, FL (11 innings) | |
| 3/10/2006 | Illinois | 14 | vs | Louisiana-Lafayette | 12 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/10/2006 | Iowa | 1 | at | Texas-San Antonio | 3 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/10/2006 | Lehigh | 10 | vs | Ohio State | 17 | Box Score | Recap | Clearwater, FL | |
| 3/10/2006 | Louisiana Tech | 13 | vs | Michigan | 7 | Box Score | Recap | Baylor Ballpark Classic, Waco, TX | |
| 3/10/2006 | Ohio State | 13 | vs | Lehigh | 6 | Box Score | Recap | Clearwater, FL | |
| 3/10/2006 | Purdue | 7 | at | Missouri | 0 | Box Score | Recap | ||
| 3/10/2006 | Vermont | 5 | at | Minnesota | 11 | Box Score | Recap | Metrodome Tournament, Minneapolis, MN | |
| 3/11/2006 | Ball State | 0 | at | Minnesota | 2 | Box Score | Recap | Metrodome Tournament, Minneapolis, MN | |
| 3/11/2006 | Illinois | 3 | at | Texas-San Antonio | 9 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/11/2006 | Iowa | 2 | vs | Notre Dame | 16 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/11/2006 | Michigan | 0 | at | Baylor | 16 | Box Score | Recap | Baylor Ballpark Classic, Waco, TX | |
| 3/11/2006 | Northern Iowa | 6 | vs | Ohio State | 9 | Box Score | Recap | Clearwater, FL | |
| 3/11/2006 | Penn State | 1 | vs | Bethune-Cookman | 2 | Box Score | Recap | Clearwater, FL | |
| 3/11/2006 | Purdue | at | Missouri | Recap | suspended to 3/12, rain (5-0 Missouri, Bottom 4) | ||||
| 3/11/2006 | Rhode Island | 7 | vs | Michigan State | 4 | Box Score | Recap | Boca Raton, FL (10 innings) | |
| 3/11/2006 | Toledo | 6 | vs | Penn State | 5 | Box Score | Recap | ||
| 3/12/2006 | Illinois | 2 | vs | Notre Dame | 4 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/12/2006 | Illinois State | 0 | at | Minnesota | 9 | Box Score | Recap | Metrodome Tournament, Minneapolis, MN | |
| 3/12/2006 | Indiana | 11 | vs | Eastern Illinois | 12 | Box Score | Recap | Bradenton, FL | |
| 3/12/2006 | Louisiana-Lafayette | 3 | vs | Iowa | 2 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/12/2006 | Michigan | 13 | vs | Pacific | 9 | Box Score | Recap | Baylor Ballpark Classic, Waco, TX | |
| 3/12/2006 | Ohio State | 9 | vs | Bethune-Cookman | 1 | Box Score | Recap | Clearwater, FL | |
| 3/12/2006 | Purdue | 2 | at | Missouri | 22 | Box Score | Recap | resumption of suspended game | |
| 3/12/2006 | Purdue | 8 | at | Missouri | 6 | Box Score | Recap | ||
| 3/13/2006 | Indiana | 3 | vs | Northern Iowa | 1 | Box Score | Recap | Bradenton, FL | |
| 3/13/2006 | Notre Dame | 6 | vs | Iowa | 2 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/13/2006 | Texas A&M | 11 | vs | Illinois | 1 | Box Score | Recap | Baseball Express Collegiate Baseball Classic, San Antonio, TX | |
| 3/14/2006 | Indiana | 5 | vs | Bradley | 6 | Box Score | Recap | 10 innings | |
| 3/14/2006 | Minnesota | 6 | at | New Orleans | 4 | Box Score | Recap | ||
| 3/14/2006 | Purdue | 7 | at | Missouri State | 5 | Box Score | Recap | ||
| 3/15/2006 | Indiana | 15 | vs | Fairfield | 2 | Box Score | Recap | Bradenton, FL | |
| 3/15/2006 | Minnesota | 15 | at | Southern | 8 | Box Score | Recap | ||
| 3/15/2006 | Purdue | 10 | at | Missouri State | 3 | Box Score | Recap | ||
| 3/15/2006 | Southern Illinois | 3 | vs | Iowa | 4 | Box Score | Recap | Irish Classic, San Antonio, TX | |
| 3/16/2006 | Indiana | 6 | vs | Eastern Kentucky | 7 | Box Score | Recap | Bradenton, FL | |
| 3/16/2006 | Iowa | 5 | vs | Notre Dame | 7 | Box Score | Recap | Irish Classic, San Antonio, TX | |
| 3/16/2006 | Iowa | 15 | vs | Southern Illinois | 9 | Box Score | Recap | Irish Classic, San Antonio, TX | |
| 3/17/2006 | George Washington | 0 | vs | Michigan | 3 | Box Score | Recap | Coca-Cola Classic, Rock Hill, SC | |
| 3/17/2006 | Iowa | 10 | vs | Notre Dame | 8 | Box Score | Recap | Irish Classic, San Antonio, TX | |
| 3/17/2006 | Michigan State | 5 | at | Ohio | 9 | Box Score | Recap | ||
| 3/17/2006 | Minnesota | 0 | at | Louisiana-Lafayette | 2 | Box Score | Recap | ||
| 3/17/2006 | Purdue | 7 | at | St. Louis | 1 | Box Score | Recap | ||
| 3/17/2006 | Vermont | 6 | vs | Indiana | 10 | Box Score | Recap | Bradenton, FL | |
| 3/18/2006 | Illinois | 13 | vs | Northern Iowa | 8 | Box Score | Recap | Bradenton, FL | |
| 3/18/2006 | Indiana | 1 | vs | Illinois-Chicago | 5 | Box Score | Recap | Bradenton, FL | |
| 3/18/2006 | Michigan | 3 | at | Winthrop | 5 | Box Score | Recap | Coca-Cola Classic, Rock Hill, SC | |
| 3/18/2006 | Michigan State | 4 | at | Ohio | 1 | Box Score | Recap | ||
| 3/18/2006 | Michigan State | 7 | at | Ohio | 6 | Box Score | Recap | ||
| 3/18/2006 | Minnesota | 3 | at | Louisiana-Lafayette | 2 | Box Score | Recap | ||
| 3/18/2006 | Northwestern | 4 | at | Santa Clara | 5 | Box Score | Recap | ||
| 3/18/2006 | Penn State | 4 | at | Furman | 2 | Box Score | Recap | ||
| 3/18/2006 | Penn State | 4 | at | Furman | 8 | Box Score | Recap | ||
| 3/18/2006 | Purdue | 4 | at | St. Louis | 0 | Box Score | Recap | ||
| 3/19/2006 | Illinois | 4 | vs | Illinois-Chicago | 2 | Box Score | Recap | Bradenton, FL | |
| 3/19/2006 | Massachusetts | 0 | vs | Ohio State | 14 | Box Score | Recap | Bradenton, FL | |
| 3/19/2006 | Michigan | 15 | vs | Wagner | 8 | Box Score | Recap | Coca-Cola Classic, Rock Hill, SC | |
| 3/19/2006 | Michigan State | 5 | at | Ohio | 7 | Box Score | Recap | ||
| 3/19/2006 | Minnesota | 1 | at | Louisiana-Lafayette | 3 | Box Score | Recap | ||
| 3/19/2006 | Northwestern | 1 | at | Santa Clara | 4 | Box Score | Recap | ||
| 3/19/2006 | Northwestern | 4 | at | Santa Clara | 10 | Box Score | Recap | ||
| 3/19/2006 | Penn State | 5 | at | Furman | 7 | Box Score | Recap | ||
| 3/19/2006 | Purdue | 5 | at | St. Louis | 6 | Box Score | Recap | ||
| 3/20/2006 | Illinois | 4 | vs | Massachusetts | 3 | Box Score | Recap | Bradenton, FL | |
| 3/20/2006 | Ohio State | 12 | vs | Cornell | 4 | Box Score | Recap | Bradenton, FL | |
| 3/21/2006 | Cornell | 0 | vs | Ohio State | 6 | Box Score | Recap | Bradenton, FL | |
| 3/21/2006 | Illinois-Chicago | 7 | vs | Ohio State | 1 | Box Score | Recap | Bradenton, FL | |
| 3/21/2006 | Valparaiso | at | Indiana | Recap | CCD, snow | ||||
| 3/22/2006 | Bucknell | at | Penn State | Recap | PPD to 4/25, cold | ||||
| 3/22/2006 | Illinois | 15 | vs | Vermont | 7 | Box Score | Recap | Bradenton, FL | |
| 3/22/2006 | Purdue | at | Indiana State | Recap | PPD to 4/5, snow | ||||
| 3/23/2006 | Illinois | 6 | vs | Cornell | 4 | Box Score | Recap | Bradenton, FL (10 innings) | |
| 3/23/2006 | Northwestern | 5 | at | Loyola Marymount | 11 | Box Score | Recap | ||
| 3/23/2006 | Ohio State | vs | Vermont | Recap | PPD to 3/24, rain (Bradenton, FL) | ||||
| 3/24/2006 | Cornell | 12 | vs | Illinois | 19 | Box Score | Recap | Bradenton, FL | |
| 3/24/2006 | Hartford | 4 | at | Indiana | 6 | Box Score | Recap | ||
| 3/24/2006 | Minnesota | 4 | at | Missouri State | 3 | Box Score | Recap | ||
| 3/24/2006 | Northwestern | 0 | at | Pepperdine | 8 | Box Score | Recap | ||
| 3/24/2006 | Oakland | 5 | at | Michigan | 14 | Box Score | Recap | ||
| 3/24/2006 | Ohio State | 6 | vs | Vermont | 5 | Box Score | Recap | Bradenton, FL | |
| 3/24/2006 | Penn State | 5 | at | Arizona State | 8 | Box Score | Recap | ||
| 3/24/2006 | Vermont | 1 | vs | Ohio State | 14 | Box Score | Recap | makeup of 3/23 game (Bradenton, FL) | |
| 3/25/2006 | Chicago State | 4 | at | Purdue | 5 | Box Score | Recap | 10 innings | |
| 3/25/2006 | Chicago State | 6 | at | Purdue | 16 | Box Score | Recap | ||
| 3/25/2006 | Hartford | 2 | at | Indiana | 4 | Box Score | Recap | ||
| 3/25/2006 | IUPU-Fort Wayne | 1 | at | Iowa | 5 | Box Score | Recap | moved from 3/24 | |
| 3/25/2006 | IUPU-Fort Wayne | 1 | at | Iowa | 0 | Box Score | Recap | 10 innings | |
| 3/25/2006 | Minnesota | 11 | at | Missouri State | 5 | Box Score | Recap | ||
| 3/25/2006 | Northwestern | 3 | at | Pepperdine | 10 | Box Score | Recap | ||
| 3/25/2006 | Oakland | 7 | at | Michigan | 8 | Box Score | Recap | ||
| 3/25/2006 | Penn State | 5 | at | Arizona State | 15 | Box Score | Recap | ||
| 3/25/2006 | Western Illinois | 0 | at | Michigan State | 7 | Box Score | Recap | ||
| 3/26/2006 | Chicago State | 0 | at | Purdue | 14 | Box Score | Recap | ||
| 3/26/2006 | Hartford | 5 | at | Indiana | 6 | Box Score | Recap | 11 innings | |
| 3/26/2006 | IUPU-Fort Wayne | 1 | at | Iowa | 11 | Box Score | Recap | ||
| 3/26/2006 | Minnesota | 4 | at | Missouri State | 5 | Box Score | Recap | 10 innings | |
| 3/26/2006 | Northwestern | 2 | at | Pepperdine | 4 | Box Score | Recap | ||
| 3/26/2006 | Oakland | 2 | at | Michigan | 3 | Box Score | Recap | ||
| 3/26/2006 | Oakland | 5 | at | Michigan | 8 | Box Score | Recap | moved from 3/25 | |
| 3/26/2006 | Penn State | 7 | at | Arizona State | 9 | Box Score | Recap | ||
| 3/26/2006 | Western Illinois | 5 | at | Michigan State | 3 | Box Score | Recap | ||
| 3/26/2006 | Western Illinois | 3 | at | Michigan State | 13 | Box Score | Recap | moved from 3/25 | |
| 3/28/2006 | Bowling Green State | 4 | at | Michigan | 7 | Box Score | Recap | ||
| 3/28/2006 | Illinois | 4 | at | Indiana State | 2 | Box Score | Recap | ||
| 3/29/2006 | Ball State | 3 | at | Purdue | 2 | Box Score | Recap | ||
| 3/29/2006 | Grand Valley State | 5 | at | Michigan State | 14 | Box Score | Recap | ||
| 3/29/2006 | Illinois State | 7 | at | Iowa | 3 | Box Score | Recap | ||
| 3/29/2006 | Indiana | 5 | at | Butler | 6 | Box Score | Recap | ||
| 3/29/2006 | Toledo | 5 | at | Ohio State | 8 | Box Score | Recap | ||
| 3/31/2006 | * | Indiana | 7 | at | Michigan State | 17 | Box Score | Recap | |
| 3/31/2006 | * | Northwestern | 2 | at | Michigan | 6 | Box Score | Recap | |
| 3/31/2006 | * | Ohio State | 12 | at | Iowa | 5 | Box Score | Recap | |
| 3/31/2006 | * | Penn State | 7 | at | Minnesota | 3 | Box Score | Recap | |
| 3/31/2006 | * | Purdue | 7 | at | Illinois | 9 | Box Score | Recap | |
| 4/1/2006 | * | Indiana | 1 | at | Michigan State | 2 | Box Score | Recap | |
| 4/1/2006 | * | Indiana | 12 | at | Michigan State | 7 | Box Score | Recap | |
| 4/1/2006 | * | Northwestern | 5 | at | Michigan | 0 | Box Score | Recap | |
| 4/1/2006 | * | Northwestern | 4 | at | Michigan | 2 | Box Score | Recap | |
| 4/1/2006 | * | Ohio State | 1 | at | Iowa | 7 | Box Score | Recap | |
| 4/1/2006 | * | Ohio State | 6 | at | Iowa | 4 | Box Score | Recap | |
| 4/1/2006 | * | Penn State | 12 | at | Minnesota | 2 | Box Score | Recap | |
| 4/1/2006 | * | Penn State | 0 | at | Minnesota | 5 | Box Score | Recap | |
| 4/1/2006 | * | Purdue | 2 | at | Illinois | 3 | Box Score | Recap | |
| 4/1/2006 | * | Purdue | 10 | at | Illinois | 4 | Box Score | Recap | |
| 4/2/2006 | * | Indiana | 8 | at | Michigan State | 9 | Box Score | Recap | 10 innings |
| 4/2/2006 | * | Northwestern | 5 | at | Michigan | 4 | Box Score | Recap | |
| 4/2/2006 | * | Ohio State | 15 | at | Iowa | 1 | Box Score | Recap | |
| 4/2/2006 | * | Penn State | 0 | at | Minnesota | 5 | Box Score | Recap | |
| 4/2/2006 | * | Purdue | 9 | at | Illinois | 4 | Box Score | Recap | |
| 4/4/2006 | Indiana | 4 | at | Evansville | 11 | Box Score | Recap | ||
| 4/4/2006 | Western Michigan | 7 | at | Illinois | 2 | Box Score | Recap | ||
| 4/5/2006 | Eastern Michigan | 3 | at | Michigan State | 6 | Box Score | Recap | ||
| 4/5/2006 | Iowa | 2 | at | Illinois State | 5 | Box Score | Recap | ||
| 4/5/2006 | Miami, Ohio | 2 | at | Ohio State | 9 | Box Score | Recap | ||
| 4/5/2006 | Michigan | 19 | at | Central Michigan | 4 | Box Score | Recap | ||
| 4/5/2006 | Minnesota | 7 | at | Northern Iowa | 3 | Box Score | Recap | ||
| 4/5/2006 | Penn State | 7 | vs | Pittsburgh | 4 | Box Score | Recap | Altoona, PA (11 innings) | |
| 4/5/2006 | Purdue | 8 | at | Indiana State | 5 | Box Score | Recap | makeup of 3/22 game | |
| 4/5/2006 | Western Michigan | 5 | at | Illinois | 16 | Box Score | Recap | ||
| 4/7/2006 | * | Illinois | at | Ohio State | Recap | PPD to 4/9, rain | |||
| 4/7/2006 | * | Indiana | at | Northwestern | Recap | PPD to 4/9, inclement weather | |||
| 4/7/2006 | * | Iowa | 6 | at | Penn State | 1 | Box Score | Recap | |
| 4/7/2006 | * | Michigan | 8 | at | Minnesota | 6 | Box Score | Recap | |
| 4/7/2006 | * | Michigan State | 1 | at | Purdue | 10 | Box Score | Recap | |
| 4/8/2006 | * | Illinois | 1 | at | Ohio State | 4 | Box Score | Recap | |
| 4/8/2006 | * | Illinois | 1 | at | Ohio State | 5 | Box Score | Recap | |
| 4/8/2006 | * | Indiana | 2 | at | Northwestern | 4 | Box Score | Recap | |
| 4/8/2006 | * | Iowa | 11 | at | Penn State | 3 | Box Score | Recap | |
| 4/8/2006 | * | Iowa | 2 | at | Penn State | 1 | Box Score | Recap | |
| 4/8/2006 | * | Michigan | 5 | at | Minnesota | 6 | Box Score | Recap | |
| 4/8/2006 | * | Michigan | 2 | at | Minnesota | 0 | Box Score | Recap | |
| 4/8/2006 | * | Michigan State | 1 | at | Purdue | 6 | Box Score | Recap | |
| 4/8/2006 | * | Michigan State | 4 | at | Purdue | 0 | Box Score | Recap | |
| 4/9/2006 | * | Illinois | 8 | at | Ohio State | 6 | Box Score | Recap | makeup of 4/7 game |
| 4/9/2006 | * | Illinois | 1 | at | Ohio State | 9 | Box Score | Recap | |
| 4/9/2006 | * | Indiana | 1 | at | Northwestern | 12 | Box Score | Recap | makeup of 4/7 game |
| 4/9/2006 | * | Indiana | 3 | at | Northwestern | 2 | Box Score | Recap | |
| 4/9/2006 | * | Iowa | 10 | at | Penn State | 11 | Box Score | Recap | 6 innings, travel curfew |
| 4/9/2006 | * | Michigan | 2 | at | Minnesota | 0 | Box Score | Recap | |
| 4/9/2006 | * | Michigan State | 3 | at | Purdue | 4 | Box Score | Recap | |
| 4/10/2006 | * | Indiana | 3 | at | Northwestern | 4 | Box Score | Recap | moved from 4/7, impending weather |
| 4/11/2006 | Illinois | 7 | at | Bradley | 8 | Box Score | Recap | ||
| 4/11/2006 | Nebraska | 16 | at | Iowa | 14 | Box Score | Recap | 13 innings | |
| 4/11/2006 | Robert Morris | 14 | at | Northwestern | 8 | Box Score | Recap | ||
| 4/12/2006 | Central Michigan | 5 | at | Ohio State | 8 | Box Score | Recap | ||
| 4/12/2006 | Duquesne | 6 | at | Penn State | 12 | Box Score | Recap | ||
| 4/12/2006 | Illinois State | 8 | at | Purdue | 9 | Box Score | Recap | ||
| 4/12/2006 | Indiana | 10 | at | Xavier | 6 | Box Score | Recap | ||
| 4/12/2006 | Minnesota | 16 | at | South Dakota State | 11 | Box Score | Recap | ||
| 4/12/2006 | Toledo | 10 | at | Michigan | 9 | Box Score | Recap | 10 innings | |
| 4/12/2006 | Western Michigan | 5 | vs | Michigan State | 7 | Box Score | Recap | Comstock Park, MI | |
| 4/14/2006 | * | Michigan State | 9 | at | Penn State | 10 | Box Score | Recap | |
| 4/14/2006 | * | Minnesota | 9 | at | Iowa | 0 | Box Score | Recap | |
| 4/14/2006 | * | Northwestern | 19 | at | Illinois | 18 | Box Score | Recap | |
| 4/14/2006 | * | Ohio State | 3 | at | Michigan | 14 | Box Score | Recap | |
| 4/14/2006 | * |