| Game Date |
| Opponent | Conference Game | Result | Commentary |
| 2/3/2006 | vs | Gonzaga |
| L 7-6 | UTPA Classic, Edinburg, TX |
| 2/4/2006 | vs | Northern Colorado |
| L 11-7 | UTPA Classic, Edinburg, TX |
| 2/5/2006 | vs | Oklahoma |
| W 21-9 | UTPA Classic, Edinburg, TX |
| 2/10/2006 |
| Texas-Pan American |
|
| PPD to 2/13, rain |
| 2/11/2006 |
| Texas-Pan American |
| W 6-1 |
|
| 2/12/2006 |
| Texas-Pan American |
| W 10-0 |
|
| 2/13/2006 |
| Texas-Pan American |
| W 11-3 | makeup of 2/10 game |
| 2/17/2006 | vs | Long Beach State |
| L 11-6 | Coca-Cola Classic, Houston, TX |
| 2/18/2006 | vs | Oklahoma |
| L 11-4 | Coca-Cola Classic, Houston, TX |
| 2/19/2006 | at | Rice |
| L 7-1 | Coca-Cola Classic, Houston, TX |
| 2/24/2006 |
| Michigan State |
| W 8-1 | Cardinal Classic, Beaumont, TX |
| 2/25/2006 |
| Kentucky |
| L 6-1 | Cardinal Classic, Beaumont, TX |
| 2/25/2006 |
| Michigan State |
|
| CCD, rain (Cardinal Classic, Beaumont, TX) |
| 2/26/2006 |
| Arkansas State |
| W 11-8 | Cardinal Classic, Beaumont, TX |
| 2/28/2006 |
| Houston |
| W 5-4 |
|
| 3/3/2006 |
| Iona |
| W 23-0 | Lamar Classic, Beaumont, TX |
| 3/4/2006 |
| Connecticut |
| W 4-0 | Lamar Classic, Beaumont, TX |
| 3/5/2006 |
| New Orleans |
| W 2-1 | Lamar Classic, Beaumont, TX (10 innings) |
| 3/7/2006 | at | Houston |
| L 4-3 |
|
| 3/10/2006 | at | Southeastern Louisiana | * | L 4-0 |
|
| 3/11/2006 | at | Southeastern Louisiana | * | W 6-1 |
|
| 3/12/2006 | at | Southeastern Louisiana | * | W 5-1 |
|
| 3/14/2006 | at | Louisiana Tech |
| L 14-5 |
|
| 3/14/2006 | at | Louisiana Tech |
| W 9-4 |
|
| 3/17/2006 |
| Texas-San Antonio | * | W 13-3 |
|
| 3/18/2006 |
| Texas-San Antonio | * | L 3-0 |
|
| 3/19/2006 |
| Texas-San Antonio | * | W 6-4 | 11 innings |
| 3/21/2006 |
| Louisiana-Lafayette |
| W 5-4 |
|
| 3/24/2006 |
| Stephen F. Austin | * | W 10-1 |
|
| 3/25/2006 |
| Stephen F. Austin | * | W 12-2 |
|
| 3/26/2006 |
| Stephen F. Austin | * | W 8-0 |
|
| 3/28/2006 |
| Texas A&M |
| L 6-5 | 10 innings |
| 3/31/2006 | at | Nicholls State | * | W 8-6 |
|
| 4/1/2006 | at | Nicholls State | * | W 8-6 |
|
| 4/2/2006 | at | Nicholls State | * | W 8-2 |
|
| 4/7/2006 | at | Texas-Arlington | * | W 10-3 |
|
| 4/8/2006 | at | Texas-Arlington | * | W 7-0 |
|
| 4/9/2006 | at | Texas-Arlington | * | W 8-5 |
|
| 4/13/2006 |
| Sam Houston State | * | L 6-2 |
|
| 4/14/2006 |
| Sam Houston State | * | W 8-1 |
|
| 4/15/2006 |
| Sam Houston State | * | W 3-0 |
|
| 4/18/2006 |
| Prairie View A&M |
| W 7-5 |
|
| 4/21/2006 |
| Louisiana-Monroe | * | W 12-2 |
|
| 4/22/2006 |
| Louisiana-Monroe | * | W 12-1 |
|
| 4/23/2006 |
| Louisiana-Monroe | * | L 10-5 |
|
| 4/25/2006 | at | Louisiana-Lafayette |
|
| CCD, rain |
| 4/28/2006 | at | Texas State | * | L 14-6 |
|
| 4/29/2006 | at | Texas State | * | W 9-3 |
|
| 4/30/2006 | at | Texas State | * | L 12-9 |
|
| 5/6/2006 | at | Northwestern State | * | L 11-8 |
|
| 5/6/2006 | at | Northwestern State | * | L 8-7 | 11 innings |
| 5/7/2006 | at | Northwestern State | * | L 5-4 |
|
| 5/10/2006 | at | Rice |
| L 11-2 |
|
| 5/12/2006 |
| Prairie View A&M |
| W 7-5 |
|
| 5/18/2006 |
| McNeese State | * | L 7-5 |
|
| 5/19/2006 |
| McNeese State | * | L 14-3 |
|
| 5/20/2006 |
| McNeese State | * | W 16-3 |
|
| 5/24/2006 |
| Texas-San Antonio | SOUTHLAND-03 | W 6-5 | 11 innings (Southland Tournament, Game 3, Beaumont, TX) |
| 5/25/2006 |
| Texas State | SOUTHLAND-06 | W 7-6 | Southland Tournament, Game 6, Beaumont, TX |
| 5/26/2006 |
| Northwestern State | SOUTHLAND-09 | L 11-1 | Southland Tournament, Game 9, Beaumont, TX |
| 5/27/2006 |
| Texas-Arlington | SOUTHLAND-10 | L 8-7 | Southland Tournament, Game 10, Beaumont, TX |
| Game Date |
| Opponent | Conference Game | Result | Commentary |
| 2/10/2006 | at | Texas A&M |
| L 10-4 | A&M ties school record 10 SB |
| 2/11/2006 | at | Texas A&M |
| L 4-3 | 13 innings |
| 2/12/2006 | at | Texas A&M |
| L 2-1 |
|
| 2/15/2006 |
| Grambling State |
| W 9-2 |
|
| 2/17/2006 |
| Tennessee-Martin |
| W 9-1 |
|
| 2/17/2006 |
| Tennessee-Martin |
| W 7-1 | moved from 2/19, impending weather |
| 2/18/2006 |
| Tennessee-Martin |
|
| PPD to 2/19, inclement weather |
| 2/19/2006 |
| Tennessee-Martin |
| W 7-2 | makeup of 2/18 game |
| 2/21/2006 |
| Centenary |
| W 6-3 |
|
| 2/22/2006 | at | Houston |
| L 12-3 |
|
| 2/25/2006 |
| Oakland |
|
| PPD to 2/26, rain |
| 2/26/2006 |
| Oakland |
| W 4-3 |
|
| 2/26/2006 |
| Oakland |
| W 15-5 |
|
| 2/28/2006 | at | Arkansas-Little Rock |
| L 13-10 |
|
| 3/3/2006 | vs | Iowa |
| L 2-0 | Louisiana-Lafayette Invitational, Lafayette, LA |
| 3/4/2006 | vs | Evansville |
| W 5-3 | Louisiana-Lafayette Invitational, Lafayette, LA |
| 3/5/2006 | at | Louisiana-Lafayette |
| W 2-0 | Louisiana-Lafayette Invitational, Lafayette, LA |
| 3/7/2006 | at | Louisiana College |
| W 10-7 |
|
| 3/10/2006 | at | Texas-Arlington | * | L 10-9 |
|
| 3/11/2006 | at | Texas-Arlington | * | L 14-1 |
|
| 3/12/2006 | at | Texas-Arlington | * | L 6-1 |
|
| 3/14/2006 | at | Grambling State |
| W 11-2 |
|
| 3/17/2006 |
| Sam Houston State | * | W 5-2 |
|
| 3/18/2006 |
| Sam Houston State | * | L 9-6 |
|
| 3/18/2006 |
| Sam Houston State | * | L 7-3 | moved from 3/19, impending weather |
| 3/24/2006 | at | Texas-San Antonio | * | L 4-3 |
|
| 3/25/2006 | at | Texas-San Antonio | * | L 6-3 |
|
| 3/26/2006 | at | Texas-San Antonio | * | W 6-1 |
|
| 3/29/2006 | at | Louisiana-Lafayette |
| W 7-5 |
|
| 3/31/2006 | at | Dallas Baptist |
| L 10-4 |
|
| 4/1/2006 | at | Dallas Baptist |
| L 9-5 |
|
| 4/4/2006 |
| Louisiana-Lafayette |
| L 3-1 |
|
| 4/7/2006 |
| Texas State | * | L 5-0 |
|
| 4/8/2006 |
| Texas State | * | L 15-2 |
|
| 4/9/2006 |
| Texas State | * | W 4-3 | 16 innings |
| 4/11/2006 | at | Louisiana State |
| L 12-0 |
|
| 4/13/2006 | at | Stephen F. Austin | * | L 3-2 |
|
| 4/14/2006 | at | Stephen F. Austin | * | W 4-3 |
|
| 4/15/2006 | at | Stephen F. Austin | * | W 5-2 |
|
| 4/18/2006 |
| Arkansas-Little Rock |
| W 13-7 |
|
| 4/21/2006 | at | Southeastern Louisiana | * | W 10-7 |
|
| 4/22/2006 | at | Southeastern Louisiana | * | W 12-7 |
|
| 4/23/2006 | at | Southeastern Louisiana | * | L 3-2 |
|
| 4/25/2006 | at | Tulane |
| L 8-3 |
|
| 4/28/2006 |
| Nicholls State | * | W 3-1 |
|
| 4/29/2006 |
| Nicholls State | * | W 5-4 |
|
| 4/30/2006 |
| Nicholls State | * | W 8-2 |
|
| 5/3/2006 |
| Louisiana-Lafayette |
| W 7-2 |
|
| 5/6/2006 |
| Lamar | * | W 11-8 |
|
| 5/6/2006 |
| Lamar | * | W 8-7 | 11 innings |
| 5/7/2006 |
| Lamar | * | W 5-4 |
|
| 5/12/2006 | at | McNeese State | * | L 12-1 |
|
| 5/13/2006 | at | McNeese State | * | L 3-2 |
|
| 5/14/2006 | at | McNeese State | * | L 9-6 |
|
| 5/16/2006 | at | Louisiana-Lafayette |
| W 13-9 |
|
| 5/18/2006 |
| Louisiana-Monroe | * | W 3-2 |
|
| 5/19/2006 |
| Louisiana-Monroe | * | W 5-4 |
|
| 5/20/2006 |
| Louisiana-Monroe | * | L 16-6 |
|
| 5/24/2006 | vs | McNeese State | SOUTHLAND-01 | W 9-1 | Southland Tournament, Game 1, Beaumont, TX |
| 5/25/2006 | vs | Texas-San Antonio | SOUTHLAND-05 | L 10-0 | Southland Tournament, Game 5, Beaumont, TX |
| 5/26/2006 | vs | Texas State | SOUTHLAND-07 | W 9-8 | Southland Tournament, Game 7, Beaumont, TX |
| 5/26/2006 | at | Lamar | SOUTHLAND-09 | W 11-1 | Southland Tournament, Game 9, Beaumont, TX |
| 5/27/2006 | vs | Texas-Arlington | SOUTHLAND-11 | L 8-2 | Southland Tournament, Game 11, Beaumont, TX (if necessary) |