| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 3/20/2008 |
| Northern Colorado | 3 | at | #1 Arizona State | 13 | FINAL | Box Score | Recap | Bob Schaefer Memorial Tournament, Tempe, AZ |
| 3/20/2008 | * | #2 Arizona |
| at | Southern California |
| Postponed | | Recap | PPD to 3/21, lighting malfunction |
| 3/20/2008 | * | #10 Texas | 22 | at | Texas Tech | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Xavier | 1 | at | #12 Kentucky | 12 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Furman | 2 | at | #21 Clemson | 14 | FINAL | Box Score | Recap | makeup of 3/19 game |
| 3/20/2008 |
| Nevada-Las Vegas | 5 | at | #23 Cal State Fullerton | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | #24 California | 9 | at | Washington State | 1 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| #29 Pepperdine |
| at | #25 Oregon State |
| Suspended | | Recap | Suspended to 3/21, inclement weather (3-0 OSU, top 5) |
| America East Conference |
| 3/20/2008 |
| Central Connecticut State |
| vs | Maryland-Baltimore County |
| Canceled | | Recap | CCD, rain (Bradenton, FL) |
| 3/20/2008 |
| Hartford | 1 | at | North Carolina-Asheville | 9 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Stony Brook | 16 | at | James Madison | 3 | FINAL | Box Score | Recap | |
| Atlantic 10 Conference |
| 3/20/2008 |
| Xavier | 1 | at | #12 Kentucky | 12 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | LaSalle | 4 | at | Richmond | 7 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Massachusetts |
| at | Duquesne |
| Postponed | | Recap | PPD to 3/21 |
| 3/20/2008 | * | St. Bonaventure | 4 | at | Fordham | 0 | FINAL | Box Score | Recap | |
| Atlantic Coast Conference |
| 3/20/2008 |
| Furman | 2 | at | #21 Clemson | 14 | FINAL | Box Score | Recap | makeup of 3/19 game |
| 3/20/2008 |
| Boston College | 12 | at | Virginia Tech | 6 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 3/20/2008 | * | Belmont | 1 | at | Kennesaw State | 3 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | East Tennessee State | 21 | at | Jacksonville | 4 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Gardner-Webb | 5 | at | Lipscomb | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Campbell | 9 | at | Stetson | 3 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 3/20/2008 |
| Army |
| vs | Ohio State |
| Canceled | | Recap | CCD, field conditions (Bradenton, FL) |
| 3/20/2008 |
| Illinois |
| vs | Northern Iowa |
| Canceled | | Recap | CCD, inclement weather (Bradenton, FL) |
| 3/20/2008 |
| Oakland | 4 | at | Michigan | 7 | FINAL | Box Score | Recap | |
| Big 12 Conference |
| 3/20/2008 | * | #10 Texas | 22 | at | Texas Tech | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Kansas | 7 | vs | Central Connecticut State | 6 | FINAL | Box Score | Recap | Bradenton, FL |
| 3/20/2008 |
| Kansas | 8 | vs | Dartmouth | 6 | FINAL | Box Score | Recap | Bradenton, FL |
| Big East Conference |
| 3/20/2008 | * | Connecticut | 5 | at | Louisville | 14 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Notre Dame | 25 | at | Georgetown | 1 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Pittsburgh | 12 | at | West Virginia | 15 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | St. John's | 12 | at | Rutgers | 5 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Villanova | 0 | at | Seton Hall | 4 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Villanova | 2 | at | Seton Hall | 3 | FINAL | Box Score | Recap | |
| Big South Conference |
| 3/20/2008 |
| Columbia | 10 | at | Liberty | 13 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Hartford | 1 | at | North Carolina-Asheville | 9 | FINAL | Box Score | Recap | |
| Big West Conference |
| 3/20/2008 |
| Nevada-Las Vegas | 5 | at | #23 Cal State Fullerton | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Cal State Northridge | 4 | at | Loyola Marymount | 5 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 3/20/2008 |
| Iona | 5 | at | Hofstra | 12 | FINAL | Box Score | Recap | makeup of 3/19 game |
| 3/20/2008 |
| Lafayette | 10 | at | Delaware | 7 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Stony Brook | 16 | at | James Madison | 3 | FINAL | Box Score | Recap | |
| Division I Independents |
| 3/20/2008 |
| Northern Colorado | 3 | at | #1 Arizona State | 13 | FINAL | Box Score | Recap | Bob Schaefer Memorial Tournament, Tempe, AZ |
| 3/20/2008 |
| Dallas Baptist | 1 | at | Oral Roberts | 5 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Elizabeth City State |
| at | North Carolina Central |
| Postponed | | | PPD to 3/21 |
| 3/20/2008 |
| Elizabeth City State |
| at | North Carolina Central |
| Postponed | | | PPD to 3/21 |
| 3/20/2008 |
| Houston Baptist | 2 | at | Texas-Pan American | 10 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| LeMoyne | 15 | at | Holy Cross | 5 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Maryland-Eastern Shore | 2 | at | Longwood | 11 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| New Jersey Tech | 11 | at | Florida Atlantic | 21 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Utah Valley State | 3 | at | Washington | 12 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Yale | 11 | at | Presbyterian | 16 | FINAL | Box Score | Recap | |
| Ivy League |
| 3/20/2008 |
| Columbia | 10 | at | Liberty | 13 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Cornell | 8 | vs | Long Island | 12 | FINAL | | Recap | Papa John's Challenge, West Palm Beach, FL |
| 3/20/2008 |
| Kansas | 8 | vs | Dartmouth | 6 | FINAL | Box Score | Recap | Bradenton, FL |
| 3/20/2008 |
| Yale | 11 | at | Presbyterian | 16 | FINAL | Box Score | Recap | |
| Metro Atlantic Athletic Conference |
| 3/20/2008 |
| Fairfield |
| at | Quinnipiac |
| Postponed | | Recap | PPD to 4/24, field conditions |
| 3/20/2008 |
| Iona | 5 | at | Hofstra | 12 | FINAL | Box Score | Recap | makeup of 3/19 game |
| 3/20/2008 |
| Monmouth |
| at | St. Peter's |
| Postponed | | Recap | PPD to 3/27, field conditions |
| Mid American Conference |
| 3/20/2008 |
| Wayne State (MI) | 8 | at | Central Michigan | 14 | FINAL | Box Score | Recap | makeup of 3/19 game |
| Mid-Eastern Athletic Conference |
| 3/20/2008 |
| Coppin State | 12 | at | Alabama State | 13 | FINAL | | | |
| 3/20/2008 |
| Maryland-Eastern Shore | 2 | at | Longwood | 11 | FINAL | Box Score | Recap | |
| Missouri Valley Conference |
| 3/20/2008 |
| Illinois |
| vs | Northern Iowa |
| Canceled | | Recap | CCD, inclement weather (Bradenton, FL) |
| Mountain West Conference |
| 3/20/2008 |
| Nevada-Las Vegas | 5 | at | #23 Cal State Fullerton | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Air Force | 6 | at | Brigham Young | 10 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | New Mexico | 2 | at | Texas Christian | 10 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | San Diego State | 7 | at | Utah | 2 | FINAL | Box Score | Recap | |
| Northeast Conference |
| 3/20/2008 |
| Central Connecticut State |
| vs | Maryland-Baltimore County |
| Canceled | | Recap | CCD, rain (Bradenton, FL) |
| 3/20/2008 |
| Cornell | 8 | vs | Long Island | 12 | FINAL | | Recap | Papa John's Challenge, West Palm Beach, FL |
| 3/20/2008 |
| Fairfield |
| at | Quinnipiac |
| Postponed | | Recap | PPD to 4/24, field conditions |
| 3/20/2008 |
| Fairleigh Dickinson | 0 | at | San Francisco | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Kansas | 7 | vs | Central Connecticut State | 6 | FINAL | Box Score | Recap | Bradenton, FL |
| 3/20/2008 |
| Monmouth |
| at | St. Peter's |
| Postponed | | Recap | PPD to 3/27, field conditions |
| 3/20/2008 |
| Mount St. Mary's | 3 | at | Bucknell | 4 | FINAL | Box Score | Recap | 10 innings |
| Pac 10 Conference |
| 3/20/2008 |
| Northern Colorado | 3 | at | #1 Arizona State | 13 | FINAL | Box Score | Recap | Bob Schaefer Memorial Tournament, Tempe, AZ |
| 3/20/2008 | * | #2 Arizona |
| at | Southern California |
| Postponed | | Recap | PPD to 3/21, lighting malfunction |
| 3/20/2008 | * | #24 California | 9 | at | Washington State | 1 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| #29 Pepperdine |
| at | #25 Oregon State |
| Suspended | | Recap | Suspended to 3/21, inclement weather (3-0 OSU, top 5) |
| 3/20/2008 |
| Utah Valley State | 3 | at | Washington | 12 | FINAL | Box Score | Recap | |
| Patriot League |
| 3/20/2008 |
| Army |
| vs | Ohio State |
| Canceled | | Recap | CCD, field conditions (Bradenton, FL) |
| 3/20/2008 |
| Belmont Abbey | 9 | at | Navy | 11 | FINAL | Box Score | Recap | makeup of 3/19 game |
| 3/20/2008 |
| Lafayette | 10 | at | Delaware | 7 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| LeMoyne | 15 | at | Holy Cross | 5 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Mount St. Mary's | 3 | at | Bucknell | 4 | FINAL | Box Score | Recap | 10 innings |
| Southeastern Conference |
| 3/20/2008 |
| Xavier | 1 | at | #12 Kentucky | 12 | FINAL | Box Score | Recap | |
| Southern Conference |
| 3/20/2008 |
| Furman | 2 | at | #21 Clemson | 14 | FINAL | Box Score | Recap | makeup of 3/19 game |
| Southland Conference |
| 3/20/2008 | * | Nicholls State | 3 | at | McNeese State | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Northwestern State | 6 | at | Southeastern Louisiana | 4 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Sam Houston State | 5 | at | Texas A&M-Corpus Christi | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Stephen F. Austin | 1 | at | Lamar | 9 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Texas-Arlington | 6 | at | Texas State | 5 | FINAL | Box Score | Recap | 10 innings |
| 3/20/2008 | * | Texas-San Antonio | 3 | at | Central Arkansas | 4 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 3/20/2008 |
| Coppin State | 12 | at | Alabama State | 13 | FINAL | | | |
| Summit League |
| 3/20/2008 |
| Dallas Baptist | 1 | at | Oral Roberts | 5 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Oakland | 4 | at | Michigan | 7 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Southern Utah | 8 | at | Portland | 3 | FINAL | Box Score | Recap | 8 innings |
| Sun Belt Conference |
| 3/20/2008 |
| New Jersey Tech | 11 | at | Florida Atlantic | 21 | FINAL | Box Score | Recap | |
| West Coast Conference |
| 3/20/2008 |
| #29 Pepperdine |
| at | #25 Oregon State |
| Suspended | | Recap | Suspended to 3/21, inclement weather (3-0 OSU, top 5) |
| 3/20/2008 |
| Cal State Northridge | 4 | at | Loyola Marymount | 5 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Fairleigh Dickinson | 0 | at | San Francisco | 6 | FINAL | Box Score | Recap | |
| 3/20/2008 |
| Southern Utah | 8 | at | Portland | 3 | FINAL | Box Score | Recap | 8 innings |
| Western Athletic Conference |
| 3/20/2008 | * | Fresno State | 0 | at | Hawaii | 4 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | Louisiana Tech | 6 | at | Nevada | 11 | FINAL | Box Score | Recap | |
| 3/20/2008 | * | San Jose State | 6 | at | New Mexico State | 7 | FINAL | Box Score | Recap | |