| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 3/28/2008 | * | Southern California | 5 | at | #1 Arizona State | 16 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #2 Miami, Florida | 7 | at | Duke | 5 | FINAL | Box Score | Recap | 10 innings |
| 3/28/2008 | * | North Carolina State | 2 | at | #3 North Carolina | 5 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #4 Florida State | 21 | at | Wake Forest | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| #5 Long Beach State | 1 | at | #28 California | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #24 UCLA | 4 | at | #6 Arizona | 3 | FINAL | Box Score | Recap | 10 innings |
| 3/28/2008 | * | #14 Kentucky | 15 | at | #7 South Carolina | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #8 Missouri | 1 | at | Texas Tech | 0 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #9 UC Irvine | 12 | at | Cal Poly | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #30 Nebraska | 14 | at | #10 Texas | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Arkansas |
| at | #11 Vanderbilt |
| Postponed | | Recap | PPD to 3/29, rain |
| 3/28/2008 | * | Southern Mississippi | 1 | at | #12 Rice | 0 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| North Dakota State | 3 | at | #13 Wichita State | 14 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Virginia Tech | 1 | at | #15 Virginia | 10 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Santa Clara | 0 | at | #16 San Diego | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #17 Mississippi | 5 | at | Alabama | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #18 Coastal Carolina | 5 | at | Liberty | 3 | FINAL | Box Score | Recap | 11 innings |
| 3/28/2008 | * | #19 Clemson | 2 | at | Maryland | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #20 Texas A&M | 13 | at | Kansas | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | UC Riverside | 6 | at | #21 Cal State Fullerton | 7 | FINAL | Box Score | Recap | 16 innings |
| 3/28/2008 | * | #22 Oklahoma State | 3 | at | Kansas State | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #23 Baylor | 2 | at | Oklahoma | 11 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Washington |
| at | #25 Oregon State |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| 3/28/2008 | * | Louisiana State | 5 | at | #26 Florida | 8 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #27 Georgia Tech |
| at | Boston College |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| 3/28/2008 | * | Washington State | 10 | at | #29 Stanford | 4 | FINAL | Box Score | Recap | |
| America East Conference |
| 3/28/2008 |
| Albany | 3 | at | Towson | 9 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Binghamton |
| at | Fairleigh Dickinson |
| Postponed | | Recap | PPD to 3/30, inclement weather |
| 3/28/2008 |
| New York Tech | 1 | at | Stony Brook | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Vermont | 3 | at | New Mexico | 12 | FINAL | Box Score | Recap | |
| Atlantic 10 Conference |
| 3/28/2008 | * | Fordham | 8 | at | St. Louis | 10 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | George Washington | 15 | at | Richmond | 11 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | North Carolina-Charlotte | 11 | at | LaSalle | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Rhode Island | 4 | at | Dayton | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Temple | 13 | at | St. Joseph's | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Xavier |
| at | Massachusetts |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| Atlantic Coast Conference |
| 3/28/2008 | * | #2 Miami, Florida | 7 | at | Duke | 5 | FINAL | Box Score | Recap | 10 innings |
| 3/28/2008 | * | North Carolina State | 2 | at | #3 North Carolina | 5 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #4 Florida State | 21 | at | Wake Forest | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Virginia Tech | 1 | at | #15 Virginia | 10 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #19 Clemson | 2 | at | Maryland | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #27 Georgia Tech |
| at | Boston College |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| Atlantic Sun Conference |
| 3/28/2008 | * | Florida Gulf Coast | 3 | at | Campbell | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Florida Gulf Coast | 13 | at | Campbell | 3 | FINAL | Box Score | Recap | moved from 3/29, impending weather |
| 3/28/2008 | * | Gardner-Webb | 13 | at | Belmont | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Jacksonville | 8 | at | South Carolina-Upstate | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Kennesaw State | 10 | at | Lipscomb | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | North Florida | 3 | at | East Tennessee State | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Stetson | 10 | at | Mercer | 11 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 3/28/2008 | * | Illinois |
| at | Michigan State |
| Postponed | | Recap | PPD to 3/30, field conditions |
| 3/28/2008 | * | Indiana | 2 | at | Minnesota | 10 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Iowa |
| at | Michigan |
| Postponed | | Recap | PPD to 3/30, field conditions |
| 3/28/2008 | * | Northwestern | 0 | at | Purdue | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Penn State | 0 | at | Ohio State | 15 | FINAL | Box Score | Recap | |
| Big 12 Conference |
| 3/28/2008 | * | #8 Missouri | 1 | at | Texas Tech | 0 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #30 Nebraska | 14 | at | #10 Texas | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #20 Texas A&M | 13 | at | Kansas | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #22 Oklahoma State | 3 | at | Kansas State | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #23 Baylor | 2 | at | Oklahoma | 11 | FINAL | Box Score | Recap | |
| Big East Conference |
| 3/28/2008 | * | Cincinnati |
| at | Notre Dame |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| 3/28/2008 | * | Georgetown | 1 | at | South Florida | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Louisville | 2 | at | Pittsburgh | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Seton Hall | 4 | at | St. John's | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Villanova | 1 | at | Connecticut | 12 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | West Virginia | 4 | at | Rutgers | 8 | FINAL | Box Score | Recap | |
| Big South Conference |
| 3/28/2008 | * | #18 Coastal Carolina | 5 | at | Liberty | 3 | FINAL | Box Score | Recap | 11 innings |
| 3/28/2008 | * | Charleston Southern | 2 | at | Radford | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | North Carolina-Asheville | 2 | at | High Point | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Winthrop | 11 | at | VMI | 3 | FINAL | Box Score | Recap | |
| Big West Conference |
| 3/28/2008 |
| #5 Long Beach State | 1 | at | #28 California | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #9 UC Irvine | 12 | at | Cal Poly | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | UC Riverside | 6 | at | #21 Cal State Fullerton | 7 | FINAL | Box Score | Recap | 16 innings |
| 3/28/2008 | * | Cal State Northridge | 5 | at | UC Santa Barbara | 9 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Pacific | 1 | at | UC Davis | 4 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 3/28/2008 | * | Delaware | 8 | at | William and Mary | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | James Madison | 6 | at | Hofstra | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | North Carolina-Wilmington | 17 | at | Virginia Commonwealth | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Northeastern | 4 | at | Georgia State | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Old Dominion | 12 | at | George Mason | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Albany | 3 | at | Towson | 9 | FINAL | Box Score | Recap | |
| Conference USA |
| 3/28/2008 | * | Southern Mississippi | 1 | at | #12 Rice | 0 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | East Carolina | 2 | at | UCF | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Memphis |
| at | Marshall |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| 3/28/2008 | * | Tulane | 8 | at | Alabama-Birmingham | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Houston | 0 | at | San Diego State | 8 | FINAL | Box Score | Recap | |
| Division I Independents |
| 3/28/2008 |
| Hawaii-Hilo | 13 | at | St. Martin's | 8 | FINAL | Box Score | Recap | 7 innings, cold |
| 3/28/2008 |
| Hawaii-Hilo |
| at | St. Martin's |
| Postponed | | | PPD to 3/29, inclement weather |
| 3/28/2008 |
| Houston Baptist | 1 | at | Dallas Baptist | 2 | FINAL | Box Score | Recap | 11 innings |
| 3/28/2008 |
| New Jersey Tech | 3 | at | Monmouth | 10 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| New York Tech | 1 | at | Stony Brook | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Savannah State | 1 | at | Bethune-Cookman | 12 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| South Dakota State | 24 | at | Northern Colorado | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Texas-Pan American | 2 | at | New Mexico State | 12 | FINAL | Box Score | Recap | |
| Horizon League |
| 3/28/2008 | * | Cleveland State |
| at | Valparaiso |
| Postponed | | Recap | PPD to 3/30, snow |
| 3/28/2008 | * | Illinois-Chicago |
| at | Wright State |
| Postponed | | Recap | PPD to 3/29, field conditions |
| 3/28/2008 | * | Wisconsin-Milwaukee | 20 | at | Butler | 10 | FINAL | Box Score | Recap | |
| Mid American Conference |
| 3/28/2008 | * | Akron |
| at | Toledo |
| Postponed | | Recap | PPD to 3/29, field conditions |
| 3/28/2008 | * | Ball State | 10 | at | Kent State | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Central Michigan |
| at | Buffalo |
| Canceled | | Recap | CCD, field conditions |
| 3/28/2008 | * | Miami, Ohio |
| at | Eastern Michigan |
| Postponed | | Recap | PPD to 3/29, field conditions |
| 3/28/2008 | * | Northern Illinois | 2 | at | Bowling Green State | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Western Michigan |
| at | Ohio |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| Mid-Eastern Athletic Conference |
| 3/28/2008 |
| Savannah State | 1 | at | Bethune-Cookman | 12 | FINAL | Box Score | Recap | |
| Missouri Valley Conference |
| 3/28/2008 |
| North Dakota State | 3 | at | #13 Wichita State | 14 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Evansville | 0 | at | Northern Iowa | 3 | FINAL | Box Score | Recap | No-hitter for UNI's Nick Kirk |
| 3/28/2008 | * | Illinois State | 0 | at | Creighton | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Indiana State | 7 | at | Bradley | 8 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Southern Illinois | 2 | at | Missouri State | 5 | FINAL | Box Score | Recap | |
| Mountain West Conference |
| 3/28/2008 | * | Air Force | 0 | at | Utah | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Texas Christian | 6 | at | Nevada-Las Vegas | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Brigham Young | 1 | at | Oral Roberts | 16 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Houston | 0 | at | San Diego State | 8 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Vermont | 3 | at | New Mexico | 12 | FINAL | Box Score | Recap | |
| Northeast Conference |
| 3/28/2008 |
| Binghamton |
| at | Fairleigh Dickinson |
| Postponed | | Recap | PPD to 3/30, inclement weather |
| 3/28/2008 |
| New Jersey Tech | 3 | at | Monmouth | 10 | FINAL | Box Score | Recap | |
| Pac 10 Conference |
| 3/28/2008 | * | Southern California | 5 | at | #1 Arizona State | 16 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| #5 Long Beach State | 1 | at | #28 California | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | #24 UCLA | 4 | at | #6 Arizona | 3 | FINAL | Box Score | Recap | 10 innings |
| 3/28/2008 | * | Washington |
| at | #25 Oregon State |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| 3/28/2008 | * | Washington State | 10 | at | #29 Stanford | 4 | FINAL | Box Score | Recap | |
| Southeastern Conference |
| 3/28/2008 | * | #14 Kentucky | 15 | at | #7 South Carolina | 3 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Arkansas |
| at | #11 Vanderbilt |
| Postponed | | Recap | PPD to 3/29, rain |
| 3/28/2008 | * | #17 Mississippi | 5 | at | Alabama | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Louisiana State | 5 | at | #26 Florida | 8 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Georgia | 2 | at | Mississippi State | 3 | FINAL | Box Score | Recap | 10 innings |
| 3/28/2008 | * | Tennessee | 6 | at | Auburn | 12 | FINAL | Box Score | Recap | |
| Southern Conference |
| 3/28/2008 | * | Appalachian State | 5 | at | The Citadel | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Elon | 15 | at | Furman | 12 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Georgia Southern | 15 | at | College of Charleston | 9 | FINAL | Box Score | Recap | GSU's David Richardson hits for cycle |
| 3/28/2008 | * | North Carolina-Greensboro | 2 | at | Western Carolina | 17 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Wofford | 13 | at | Davidson | 4 | FINAL | Box Score | Recap | |
| Southland Conference |
| 3/28/2008 | * | Central Arkansas | 0 | at | Lamar | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Nicholls State | 3 | at | Texas A&M-Corpus Christi | 9 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Northwestern State | 12 | at | Stephen F. Austin | 10 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Southeastern Louisiana | 4 | at | McNeese State | 2 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Texas State | 2 | at | Sam Houston State | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Texas-Arlington | 3 | at | Texas-San Antonio | 5 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 3/28/2008 | * | Alcorn State | 3 | at | Jackson State | 4 | FINAL | Box Score | Recap | 7 innings |
| 3/28/2008 | * | Alcorn State | 6 | at | Jackson State | 1 | FINAL | Box Score | Recap | 7 innings |
| 3/28/2008 | * | Texas Southern | 15 | at | Arkansas-Pine Bluff | 2 | FINAL | Box Score | | 7 innings |
| Summit League |
| 3/28/2008 |
| North Dakota State | 3 | at | #13 Wichita State | 14 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Brigham Young | 1 | at | Oral Roberts | 16 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Cal State Dominguez Hills | 6 | at | Southern Utah | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Cal State Dominguez Hills | 12 | at | Southern Utah | 13 | FINAL | Box Score | Recap | 7 innings |
| 3/28/2008 |
| South Dakota State | 24 | at | Northern Colorado | 7 | FINAL | Box Score | Recap | |
| Sun Belt Conference |
| 3/28/2008 | * | Arkansas State | 9 | at | South Alabama | 17 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Arkansas-Little Rock | 0 | at | Middle Tennessee State | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Florida Atlantic | 6 | at | Louisiana-Monroe | 7 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Florida International | 9 | at | Louisiana-Lafayette | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | New Orleans | 6 | at | Troy | 1 | FINAL | Box Score | Recap | |
| West Coast Conference |
| 3/28/2008 | * | Santa Clara | 0 | at | #16 San Diego | 1 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Loyola Marymount |
| at | Portland |
| Postponed | | Recap | PPD to 3/29, rain |
| 3/28/2008 | * | Pepperdine |
| at | Gonzaga |
| Postponed | | Recap | PPD to 3/29, inclement weather |
| 3/28/2008 | * | San Francisco | 2 | at | St. Mary's | 0 | FINAL | Box Score | Recap | |
| Western Athletic Conference |
| 3/28/2008 | * | Hawaii | 2 | at | Cal State Sacramento | 4 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | Nevada | 4 | at | Fresno State | 12 | FINAL | Box Score | Recap | |
| 3/28/2008 | * | San Jose State | 11 | at | Louisiana Tech | 6 | FINAL | Box Score | Recap | |
| 3/28/2008 |
| Texas-Pan American | 2 | at | New Mexico State | 12 | FINAL | Box Score | Recap | |