| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/2/2008 |
| Wofford | 4 | at | #1 Arizona State | 12 | FINAL | Box Score | Recap | 7 innings, travel curfew |
| 4/2/2008 |
| #2 Miami, Florida | 13 | at | Florida International | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| #3 Florida State | 7 | at | Jacksonville | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Appalachian State | 0 | at | #4 North Carolina | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| #6 Vanderbilt | 6 | at | Middle Tennessee State | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Davidson | 2 | at | #7 South Carolina | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Oral Roberts | 8 | at | #8 Wichita State | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Lincoln (MO) | 2 | at | #10 Missouri | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Towson | 7 | at | #12 Virginia | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas Southern | 4 | at | #13 Texas | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Western Kentucky | 3 | at | #14 Kentucky | 7 | FINAL | Box Score | Recap | 300th career win for UK's John Cohen |
| 4/2/2008 |
| Dallas Baptist | 3 | at | #15 Rice | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Stephen F. Austin | 4 | at | #16 Texas A&M | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Georgia | 6 | at | #17 Clemson | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Southern California | 3 | at | #18 San Diego | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Fresno State | 4 | at | #20 California | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| #21 Coastal Carolina | 9 | at | Wake Forest | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| East Tennessee State | 4 | at | #24 Georgia Tech | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Florida | 11 | at | #25 Florida | 10 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Memphis | 4 | at | #27 Mississippi | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas-San Antonio | 11 | at | #29 Baylor | 7 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/2/2008 |
| Manhattan |
| at | Albany |
| Postponed | | Recap | PPD to 4/15 |
| 4/2/2008 |
| Marist |
| at | Binghamton |
| Canceled | | Recap | CCD |
| 4/2/2008 |
| Stony Brook | 4 | at | Hofstra | 8 | FINAL | Box Score | Recap | |
| Atlantic 10 Conference |
| 4/2/2008 |
| Buffalo | 0 | at | St. Bonaventure | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Buffalo | 1 | at | St. Bonaventure | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Dayton | 2 | at | Ball State | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Duquesne | 7 | at | Youngstown State | 8 | FINAL | Box Score | Recap | 14 innings |
| 4/2/2008 |
| Fordham | 10 | at | Fairfield | 9 | FINAL | Box Score | Recap | 13 innings |
| 4/2/2008 |
| Georgetown | 4 | at | George Washington | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Indiana State | 5 | at | Xavier | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Carolina-Charlotte | 5 | at | Tennessee | 12 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Rhode Island | 3 | at | Brown | 11 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Rhode Island | 8 | at | Brown | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Rider | 14 | at | Temple | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| St. Joseph's | 2 | at | Pennsylvania | 6 | FINAL | Box Score | Recap | 7 innings (makeup of 4/1 game (Liberty Bell Classic)) |
| 4/2/2008 |
| St. Joseph's | 5 | at | Pennsylvania | 16 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| St. Louis | 2 | at | Illinois | 9 | FINAL | Box Score | Recap | |
| Atlantic Coast Conference |
| 4/2/2008 |
| #2 Miami, Florida | 13 | at | Florida International | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| #3 Florida State | 7 | at | Jacksonville | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Appalachian State | 0 | at | #4 North Carolina | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Towson | 7 | at | #12 Virginia | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Georgia | 6 | at | #17 Clemson | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| #21 Coastal Carolina | 9 | at | Wake Forest | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| East Tennessee State | 4 | at | #24 Georgia Tech | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Boston College | 10 | at | Connecticut | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Elon | 0 | at | North Carolina State | 12 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| George Mason | 5 | at | Maryland | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Longwood | 7 | at | Virginia Tech | 8 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 4/2/2008 |
| #3 Florida State | 7 | at | Jacksonville | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| East Tennessee State | 4 | at | #24 Georgia Tech | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Florida | 11 | at | #25 Florida | 10 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Belmont | 3 | at | Murray State | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Belmont | 4 | at | Murray State | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Campbell | 2 | at | East Carolina | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Florida Gulf Coast | 6 | at | UCF | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| High Point | 4 | at | South Carolina-Upstate | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Kennesaw State | 7 | at | Georgia Southern | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Lipscomb | 8 | at | Tennessee-Martin | 9 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| The Citadel | 5 | at | Mercer | 9 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 4/2/2008 |
| Bucknell | 3 | at | Penn State | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Eastern Michigan | 3 | at | Michigan State | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Illinois State | 7 | at | Iowa | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Miami, Ohio | 2 | at | Indiana | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Michigan | 3 | at | Central Michigan | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Purdue | 4 | at | Louisville | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| St. Louis | 2 | at | Illinois | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Toledo | 0 | at | Ohio State | 13 | FINAL | Box Score | Recap | |
| Big 12 Conference |
| 4/2/2008 |
| Lincoln (MO) | 2 | at | #10 Missouri | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas Southern | 4 | at | #13 Texas | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Stephen F. Austin | 4 | at | #16 Texas A&M | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas-San Antonio | 11 | at | #29 Baylor | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Central Arkansas | 6 | at | Kansas State | 13 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| St. Mary (KS) | 0 | at | Kansas | 13 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas A&M-Corpus Christi | 5 | at | Texas Tech | 10 | FINAL | Box Score | Recap | 1,500th career win for TT's Larry Hays |
| Big East Conference |
| 4/2/2008 |
| Bethune-Cookman |
| at | South Florida |
| Postponed | | Recap | PPD, inclement weather |
| 4/2/2008 |
| Boston College | 10 | at | Connecticut | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Coppin State | 2 | at | Villanova | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Fairleigh Dickinson | 4 | at | Seton Hall | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Georgetown | 4 | at | George Washington | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Kent State | 7 | at | Pittsburgh | 0 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Purdue | 4 | at | Louisville | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Rutgers | 5 | at | Monmouth | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| St. John's | 5 | at | New York Tech | 4 | FINAL | Box Score | Recap | |
| Big South Conference |
| 4/2/2008 |
| #21 Coastal Carolina | 9 | at | Wake Forest | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Charleston Southern | 5 | at | Savannah State | 1 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| High Point | 4 | at | South Carolina-Upstate | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Norfolk State | 8 | at | Liberty | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Carolina-Asheville | 7 | at | Western Carolina | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Radford | 3 | at | James Madison | 7 | FINAL | Box Score | Recap | 500th career win for JMU's Joe McFarland |
| 4/2/2008 |
| VMI | 7 | at | Old Dominion | 3 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Winthrop | 4 | at | College of Charleston | 5 | FINAL | Box Score | Recap | 8 innings, rain |
| Big West Conference |
| 4/2/2008 |
| Pacific | 3 | at | Santa Clara | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| UC Santa Barbara | 3 | at | Pepperdine | 14 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/2/2008 |
| Towson | 7 | at | #12 Virginia | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Delaware | 4 | at | Lafayette | 9 | FINAL | Box Score | Recap | makeup of 4/1 game (Liberty Bell Classic) |
| 4/2/2008 |
| George Mason | 5 | at | Maryland | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Georgia State | 6 | at | Samford | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Radford | 3 | at | James Madison | 7 | FINAL | Box Score | Recap | 500th career win for JMU's Joe McFarland |
| 4/2/2008 |
| Stony Brook | 4 | at | Hofstra | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| VMI | 7 | at | Old Dominion | 3 | FINAL | Box Score | Recap | |
| Conference USA |
| 4/2/2008 |
| Dallas Baptist | 3 | at | #15 Rice | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Memphis | 4 | at | #27 Mississippi | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Alabama | 5 | at | Alabama-Birmingham | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Campbell | 2 | at | East Carolina | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Florida Gulf Coast | 6 | at | UCF | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Marshall | 3 | at | Morehead State | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Troy | 5 | at | Southern Mississippi | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Tulane | 11 | at | Nicholls State | 2 | FINAL | Box Score | Recap | |
| Division I Independents |
| 4/2/2008 |
| Dallas Baptist | 3 | at | #15 Rice | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Charleston Southern | 5 | at | Savannah State | 1 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Chicago State | 2 | at | Eastern Illinois | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| LeMoyne |
| at | Cornell |
| Postponed | | Recap | PPD to 4/3, scheduling conflict |
| 4/2/2008 |
| Longwood | 7 | at | Virginia Tech | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| New Jersey Tech |
| at | Lafayette |
| Canceled | | Recap | CCD, scheduling conflict |
| 4/2/2008 |
| Presbyterian | 7 | at | Furman | 9 | FINAL | Box Score | Recap | 10 innings (makeup of 4/1 game) |
| 4/2/2008 |
| Presbyterian | 9 | at | Furman | 10 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| St. John's | 5 | at | New York Tech | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Utah | 0 | at | Utah Valley State | 8 | FINAL | Box Score | Recap | |
| Horizon League |
| 4/2/2008 |
| Butler | 14 | at | Marian (IN) | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Cleveland State | 8 | at | Ohio | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Duquesne | 7 | at | Youngstown State | 8 | FINAL | Box Score | Recap | 14 innings |
| 4/2/2008 |
| Illinois Tech | 4 | at | Valparaiso | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Illinois-Chicago | 1 | at | Bradley | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Wisconsin-Milwaukee | 2 | at | Northern Illinois | 3 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Wright State | 11 | at | Bowling Green State | 10 | FINAL | Box Score | Recap | |
| Ivy League |
| 4/2/2008 |
| Dartmouth | 8 | at | Siena | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Harvard | 3 | at | Holy Cross | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| LeMoyne |
| at | Cornell |
| Postponed | | Recap | PPD to 4/3, scheduling conflict |
| 4/2/2008 |
| Rhode Island | 3 | at | Brown | 11 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Rhode Island | 8 | at | Brown | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| St. Joseph's | 2 | at | Pennsylvania | 6 | FINAL | Box Score | Recap | 7 innings (makeup of 4/1 game (Liberty Bell Classic)) |
| 4/2/2008 |
| St. Joseph's | 5 | at | Pennsylvania | 16 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Yale | 19 | at | Quinnipiac | 13 | FINAL | Box Score | Recap | |
| Metro Atlantic Athletic Conference |
| 4/2/2008 |
| Canisius | 7 | at | Mercyhurst | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Dartmouth | 8 | at | Siena | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Fordham | 10 | at | Fairfield | 9 | FINAL | Box Score | Recap | 13 innings |
| 4/2/2008 |
| Manhattan |
| at | Albany |
| Postponed | | Recap | PPD to 4/15 |
| 4/2/2008 |
| Manhattan | 15 | at | Wagner | 0 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Marist |
| at | Binghamton |
| Canceled | | Recap | CCD |
| 4/2/2008 |
| Rider | 14 | at | Temple | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Sacred Heart | 14 | at | Iona | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| St. Peter's | 17 | at | Long Island | 11 | FINAL | Box Score | Recap | |
| Mid American Conference |
| 4/2/2008 |
| Buffalo | 0 | at | St. Bonaventure | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Buffalo | 1 | at | St. Bonaventure | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Cleveland State | 8 | at | Ohio | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Dayton | 2 | at | Ball State | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Eastern Michigan | 3 | at | Michigan State | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Kent State | 7 | at | Pittsburgh | 0 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Malone | 2 | at | Akron | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Miami, Ohio | 2 | at | Indiana | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Michigan | 3 | at | Central Michigan | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Toledo | 0 | at | Ohio State | 13 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Wayne State (MI) | 1 | at | Western Michigan | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Wisconsin-Milwaukee | 2 | at | Northern Illinois | 3 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Wright State | 11 | at | Bowling Green State | 10 | FINAL | Box Score | Recap | |
| Mid-Eastern Athletic Conference |
| 4/2/2008 |
| Bethune-Cookman |
| at | South Florida |
| Postponed | | Recap | PPD, inclement weather |
| 4/2/2008 |
| Coppin State | 2 | at | Villanova | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Norfolk State | 8 | at | Liberty | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Carolina A&T | 10 | at | North Carolina-Greensboro | 7 | FINAL | Box Score | Recap | |
| Missouri Valley Conference |
| 4/2/2008 |
| Oral Roberts | 8 | at | #8 Wichita State | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Grand View | 3 | at | Northern Iowa | 17 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Illinois State | 7 | at | Iowa | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Illinois-Chicago | 1 | at | Bradley | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Indiana State | 5 | at | Xavier | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Southeast Missouri State | 7 | at | Evansville | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Southern Illinois | 10 | at | Arkansas State | 3 | FINAL | Box Score | Recap | |
| Mountain West Conference |
| 4/2/2008 |
| Brigham Young | 6 | at | Southern Utah | 18 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Doane | 13 | at | Air Force | 37 | FINAL | Box Score | Recap | AF's Matt Alexander hits for cycle, 11 RBI |
| 4/2/2008 |
| Texas Christian | 12 | at | Texas State | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Utah | 0 | at | Utah Valley State | 8 | FINAL | Box Score | Recap | |
| Northeast Conference |
| 4/2/2008 |
| Fairleigh Dickinson | 4 | at | Seton Hall | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Manhattan | 15 | at | Wagner | 0 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Rutgers | 5 | at | Monmouth | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Sacred Heart | 14 | at | Iona | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| St. Peter's | 17 | at | Long Island | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Yale | 19 | at | Quinnipiac | 13 | FINAL | Box Score | Recap | |
| Ohio Valley Conference |
| 4/2/2008 |
| Austin Peay State | 2 | at | Mississippi State | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Belmont | 3 | at | Murray State | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Belmont | 4 | at | Murray State | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| Chicago State | 2 | at | Eastern Illinois | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Georgetown (KY) | 12 | at | Eastern Kentucky | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Georgia State | 6 | at | Samford | 11 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Lipscomb | 8 | at | Tennessee-Martin | 9 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Marshall | 3 | at | Morehead State | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Southeast Missouri State | 7 | at | Evansville | 8 | FINAL | Box Score | Recap | |
| Pac 10 Conference |
| 4/2/2008 |
| Wofford | 4 | at | #1 Arizona State | 12 | FINAL | Box Score | Recap | 7 innings, travel curfew |
| 4/2/2008 |
| Southern California | 3 | at | #18 San Diego | 2 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Fresno State | 4 | at | #20 California | 5 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/2/2008 |
| Bucknell | 3 | at | Penn State | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Delaware | 4 | at | Lafayette | 9 | FINAL | Box Score | Recap | makeup of 4/1 game (Liberty Bell Classic) |
| 4/2/2008 |
| Harvard | 3 | at | Holy Cross | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| New Jersey Tech |
| at | Lafayette |
| Canceled | | Recap | CCD, scheduling conflict |
| Southeastern Conference |
| 4/2/2008 |
| #6 Vanderbilt | 6 | at | Middle Tennessee State | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Davidson | 2 | at | #7 South Carolina | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Western Kentucky | 3 | at | #14 Kentucky | 7 | FINAL | Box Score | Recap | 300th career win for UK's John Cohen |
| 4/2/2008 |
| Georgia | 6 | at | #17 Clemson | 4 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Florida | 11 | at | #25 Florida | 10 | FINAL | Box Score | Recap | 10 innings |
| 4/2/2008 |
| Memphis | 4 | at | #27 Mississippi | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Alabama | 5 | at | Alabama-Birmingham | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Austin Peay State | 2 | at | Mississippi State | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Centenary | 0 | at | Louisiana State | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Mississippi Valley State |
| at | Arkansas |
| Postponed | | Recap | PPD, inclement weather |
| 4/2/2008 |
| North Carolina-Charlotte | 5 | at | Tennessee | 12 | FINAL | Box Score | Recap | |
| Southern Conference |
| 4/2/2008 |
| Wofford | 4 | at | #1 Arizona State | 12 | FINAL | Box Score | Recap | 7 innings, travel curfew |
| 4/2/2008 |
| Appalachian State | 0 | at | #4 North Carolina | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Davidson | 2 | at | #7 South Carolina | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Elon | 0 | at | North Carolina State | 12 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Kennesaw State | 7 | at | Georgia Southern | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Carolina A&T | 10 | at | North Carolina-Greensboro | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| North Carolina-Asheville | 7 | at | Western Carolina | 10 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Presbyterian | 7 | at | Furman | 9 | FINAL | Box Score | Recap | 10 innings (makeup of 4/1 game) |
| 4/2/2008 |
| Presbyterian | 9 | at | Furman | 10 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| The Citadel | 5 | at | Mercer | 9 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Winthrop | 4 | at | College of Charleston | 5 | FINAL | Box Score | Recap | 8 innings, rain |
| Southland Conference |
| 4/2/2008 |
| Stephen F. Austin | 4 | at | #16 Texas A&M | 5 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas-San Antonio | 11 | at | #29 Baylor | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Central Arkansas | 6 | at | Kansas State | 13 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Louisiana Tech |
| at | Northwestern State |
| Postponed | | Recap | PPD, field conditions |
| 4/2/2008 |
| Louisiana-Lafayette |
| at | Southeastern Louisiana |
| Postponed | | Recap | PPD to 4/23, inclement weather |
| 4/2/2008 |
| Louisiana-Monroe | 9 | at | McNeese State | 6 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Prairie View A&M | 7 | at | Sam Houston State | 14 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Texas A&M-Corpus Christi | 5 | at | Texas Tech | 10 | FINAL | Box Score | Recap | 1,500th career win for TT's Larry Hays |
| 4/2/2008 |
| Texas Christian | 12 | at | Texas State | 8 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Tulane | 11 | at | Nicholls State | 2 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 4/2/2008 |
| Texas Southern | 4 | at | #13 Texas | 7 | FINAL | Box Score | Recap | |
| 4/2/2008 |
| Grambling State | 11 | at | Jarvis Christian | 9 | FINAL | Box Score | | |
| 4/2/2008 |
| Lane |
| at | Arkansas-Pine Bluff |
| Canceled | | | CCD |
| 4/2/2008 |
| Lane |
| at | Arkansas-Pine Bluff |
| Postponed | | | PPD to 4/8 |
| 4/2/2008 |
| LeMoyne-Owen | 4 | at | Jackson State | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/2/2008 |
| LeMoyne-Owen | |