| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/8/2008 |
| Florida Gulf Coast | 2 | at | #1 Miami, Florida | 4 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| Elon | 2 | at | #4 North Carolina | 0 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #5 Wichita State | 4 | at | Kansas State | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #6 UC Irvine | 6 | at | UCLA | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Lamar | 5 | at | #7 Rice | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #8 Texas A&M | 13 | at | Houston | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Louisville | 6 | at | #9 Kentucky | 7 | FINAL | Box Score | Recap | 12 innings |
| 4/8/2008 |
| Western Carolina | 6 | at | #10 South Carolina | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas State | 3 | vs | #11 Texas | 5 | FINAL | Box Score | Recap | 500th win at UT for Augie Garrido (Round Rock, TX) |
| 4/8/2008 |
| Western Kentucky | 1 | at | #13 Vanderbilt | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #14 Nebraska |
| at | Iowa |
| Canceled | | Recap | CCD, inclement weather |
| 4/8/2008 |
| #15 Cal State Fullerton | 4 | at | Southern California | 5 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| #16 Long Beach State | 3 | at | Loyola Marymount | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #18 San Diego | 11 | at | UC Riverside | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Longwood | 0 | at | #19 Virginia | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Western Illinois | 1 | at | #20 Oklahoma State | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #22 Arizona | 11 | at | San Diego State | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| South Alabama | 5 | at | #23 Mississippi | 6 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Winthrop | 5 | at | #24 Georgia | 1 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #28 North Carolina-Wilmington | 5 | at | North Carolina State | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Florida | 3 | at | #29 Florida | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas Christian | 4 | at | #30 Baylor | 3 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/8/2008 |
| Albany | 4 | at | Marist | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Navy | 7 | at | Maryland-Baltimore County | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Vermont | 2 | at | Siena | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Vermont | 0 | at | Siena | 4 | FINAL | Box Score | Recap | 7 innings |
| Atlantic 10 Conference |
| 4/8/2008 |
| Boston College | 7 | at | Rhode Island | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Connecticut | 13 | at | Massachusetts | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Dayton | 7 | at | Bowling Green State | 2 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Duquesne | 8 | at | Pittsburgh | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Fordham | 13 | at | New Jersey Tech | 10 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| George Mason | 15 | at | George Washington | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Carolina A&T | 1 | at | North Carolina-Charlotte | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Carolina-Charlotte | 8 | at | North Carolina A&T | 7 | FINAL | Box Score | Recap | Resumption of 3/19 game |
| 4/8/2008 |
| St. Bonaventure | 8 | at | Niagara | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| St. Bonaventure | 12 | at | Niagara | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| St. John's | 3 | at | Temple | 2 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| St. Louis | 3 | at | Missouri State | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Xavier | 8 | at | Ohio | 5 | FINAL | Box Score | Recap | |
| Atlantic Coast Conference |
| 4/8/2008 |
| Florida Gulf Coast | 2 | at | #1 Miami, Florida | 4 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| Elon | 2 | at | #4 North Carolina | 0 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Longwood | 0 | at | #19 Virginia | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #28 North Carolina-Wilmington | 5 | at | North Carolina State | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Boston College | 7 | at | Rhode Island | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Coppin State | 1 | at | Maryland | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Davidson | 4 | at | Virginia Tech | 5 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 4/8/2008 |
| Florida Gulf Coast | 2 | at | #1 Miami, Florida | 4 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| North Florida | 3 | at | #29 Florida | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Appalachian State | 6 | at | South Carolina-Upstate | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Bethune-Cookman | 4 | at | Stetson | 16 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| East Tennessee State | 17 | at | Radford | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Gardner-Webb | 10 | at | Furman | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| High Point | 9 | at | Campbell | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Jacksonville | 6 | at | Georgia Southern | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Lambuth | 10 | at | Belmont | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Lipscomb | 5 | at | Middle Tennessee State | 11 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Mercer | 11 | at | Florida A&M | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Presbyterian | 1 | at | Kennesaw State | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Presbyterian | 0 | at | Kennesaw State | 6 | FINAL | Box Score | Recap | 7 innings (moved from 4/9) |
| Big 10 Conference |
| 4/8/2008 |
| #14 Nebraska |
| at | Iowa |
| Canceled | | Recap | CCD, inclement weather |
| 4/8/2008 |
| Chicago State | 0 | at | Northwestern | 13 | FINAL | Box Score | Recap | 5 innings, rain |
| 4/8/2008 |
| Illinois |
| at | Bradley |
| Canceled | | Recap | CCD, rain |
| Big 12 Conference |
| 4/8/2008 |
| #5 Wichita State | 4 | at | Kansas State | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #8 Texas A&M | 13 | at | Houston | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas State | 3 | vs | #11 Texas | 5 | FINAL | Box Score | Recap | 500th win at UT for Augie Garrido (Round Rock, TX) |
| 4/8/2008 |
| #14 Nebraska |
| at | Iowa |
| Canceled | | Recap | CCD, inclement weather |
| 4/8/2008 |
| Western Illinois | 1 | at | #20 Oklahoma State | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas Christian | 4 | at | #30 Baylor | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| New Mexico | 0 | at | Texas Tech | 10 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Northern Colorado |
| at | Kansas |
| Postponed | | Recap | PPD to 4/9, rain |
| Big East Conference |
| 4/8/2008 |
| Louisville | 6 | at | #9 Kentucky | 7 | FINAL | Box Score | Recap | 12 innings |
| 4/8/2008 |
| Cincinnati | 13 | at | Miami, Ohio | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Connecticut | 13 | at | Massachusetts | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Duquesne | 8 | at | Pittsburgh | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Georgetown |
| at | Maryland-Eastern Shore |
| Postponed | | | PPD |
| 4/8/2008 |
| Pennsylvania | 2 | at | Villanova | 16 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Rutgers | 5 | at | Columbia | 4 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| South Florida | 3 | at | UCF | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| St. John's | 3 | at | Temple | 2 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Valparaiso | 6 | at | Notre Dame | 8 | FINAL | Box Score | Recap | |
| Big South Conference |
| 4/8/2008 |
| Winthrop | 5 | at | #24 Georgia | 1 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| East Tennessee State | 17 | at | Radford | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| High Point | 9 | at | Campbell | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| James Madison | 4 | at | Liberty | 0 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| The Citadel | 7 | at | Charleston Southern | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Virginia Commonwealth | 5 | at | VMI | 3 | FINAL | Box Score | Recap | |
| Big West Conference |
| 4/8/2008 |
| #6 UC Irvine | 6 | at | UCLA | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| #15 Cal State Fullerton | 4 | at | Southern California | 5 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| #16 Long Beach State | 3 | at | Loyola Marymount | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #18 San Diego | 11 | at | UC Riverside | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Cal Poly | 10 | at | Pepperdine | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Nevada | 3 | at | Pacific | 14 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| UC Santa Barbara | 6 | at | Cal State Northridge | 5 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/8/2008 |
| #28 North Carolina-Wilmington | 5 | at | North Carolina State | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Bucknell | 5 | at | Towson | 14 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Delaware State | 10 | at | Delaware | 6 | FINAL | Box Score | Recap | 200th career win for DSU's J.P. Blandin |
| 4/8/2008 |
| George Mason | 15 | at | George Washington | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Georgia State | 6 | at | Auburn | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| James Madison | 4 | at | Liberty | 0 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| New York Tech | 6 | at | Hofstra | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Northeastern | 2 | at | Holy Cross | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Old Dominion | 2 | at | East Carolina | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Virginia Commonwealth | 5 | at | VMI | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| William and Mary |
| at | Norfolk State |
| Canceled | | Recap | CCD, field conditions |
| Conference USA |
| 4/8/2008 |
| Lamar | 5 | at | #7 Rice | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| #8 Texas A&M | 13 | at | Houston | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Alabama-Birmingham | 15 | at | Alabama A&M | 2 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Marshall | 9 | at | Morehead State | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Mississippi State | 8 | at | Memphis | 9 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Nicholls State | 1 | at | Tulane | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Old Dominion | 2 | at | East Carolina | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| South Florida | 3 | at | UCF | 6 | FINAL | Box Score | Recap | |
| Division I Independents |
| 4/8/2008 |
| Longwood | 0 | at | #19 Virginia | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Chicago State | 0 | at | Northwestern | 13 | FINAL | Box Score | Recap | 5 innings, rain |
| 4/8/2008 |
| Dallas Baptist | 2 | at | Louisiana-Monroe | 1 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Fordham | 13 | at | New Jersey Tech | 10 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| New York Tech | 6 | at | Hofstra | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Carolina Central |
| at | St. Paul's |
| Canceled | | | CCD |
| 4/8/2008 |
| North Carolina Central |
| at | St. Paul's |
| Canceled | | | CCD |
| 4/8/2008 |
| Northern Colorado |
| at | Kansas |
| Postponed | | Recap | PPD to 4/9, rain |
| 4/8/2008 |
| Presbyterian | 1 | at | Kennesaw State | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Presbyterian | 0 | at | Kennesaw State | 6 | FINAL | Box Score | Recap | 7 innings (moved from 4/9) |
| 4/8/2008 |
| Savannah State | 1 | at | College of Charleston | 11 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Southern Utah | 8 | at | Utah Valley State | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Southern Utah | 1 | at | Utah Valley State | 3 | FINAL | Box Score | Recap | makeup of 4/8 game |
| 4/8/2008 |
| Texas-Pan American | 6 | at | Texas A&M-Corpus Christi | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas-Pan American | 4 | at | Texas A&M-Corpus Christi | 6 | FINAL | Box Score | Recap | |
| Horizon League |
| 4/8/2008 |
| Cleveland State | 15 | at | Canisius | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Illinois-Chicago | 7 | at | Central Michigan | 8 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Indiana Tech | 11 | at | Butler | 17 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Urbana | 3 | at | Wright State | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Valparaiso | 6 | at | Notre Dame | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Youngstown State | 5 | at | Toledo | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Youngstown State | 10 | at | Toledo | 4 | FINAL | Box Score | Recap | 7 innings |
| Ivy League |
| 4/8/2008 | * | Harvard | 5 | at | Cornell | 6 | FINAL | Box Score | Recap | 7 innings (makeup of 3/31 game) |
| 4/8/2008 | * | Harvard | 2 | at | Cornell | 1 | FINAL | Box Score | Recap | makeup of 3/31 game |
| 4/8/2008 |
| Brown | 12 | at | Quinnipiac | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Monmouth | 7 | at | Princeton | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Pennsylvania | 2 | at | Villanova | 16 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Rutgers | 5 | at | Columbia | 4 | FINAL | Box Score | Recap | 11 innings |
| Metro Atlantic Athletic Conference |
| 4/8/2008 |
| Albany | 4 | at | Marist | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Cleveland State | 15 | at | Canisius | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Fairfield | 1 | at | Central Connecticut State | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Iona | 5 | at | Army | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Rider | 6 | at | Long Island | 2 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| St. Bonaventure | 8 | at | Niagara | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| St. Bonaventure | 12 | at | Niagara | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Vermont | 2 | at | Siena | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Vermont | 0 | at | Siena | 4 | FINAL | Box Score | Recap | 7 innings |
| Mid American Conference |
| 4/8/2008 |
| Ball State | 24 | at | IUPU-Fort Wayne | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Cincinnati | 13 | at | Miami, Ohio | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Dayton | 7 | at | Bowling Green State | 2 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Illinois-Chicago | 7 | at | Central Michigan | 8 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Northern Illinois |
| at | Illinois State |
| Canceled | | Recap | CCD, rain |
| 4/8/2008 |
| Oakland | 4 | at | Western Michigan | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Saginaw Valley | 9 | at | Eastern Michigan | 5 | FINAL | Box Score | Recap | makeup of 3/19 game |
| 4/8/2008 |
| Wooster | 4 | at | Kent State | 15 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Xavier | 8 | at | Ohio | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Youngstown State | 5 | at | Toledo | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Youngstown State | 10 | at | Toledo | 4 | FINAL | Box Score | Recap | 7 innings |
| Mid-Eastern Athletic Conference |
| 4/8/2008 |
| Bethune-Cookman | 4 | at | Stetson | 16 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Coppin State | 1 | at | Maryland | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Delaware State | 10 | at | Delaware | 6 | FINAL | Box Score | Recap | 200th career win for DSU's J.P. Blandin |
| 4/8/2008 |
| Georgetown |
| at | Maryland-Eastern Shore |
| Postponed | | | PPD |
| 4/8/2008 |
| Mercer | 11 | at | Florida A&M | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Carolina A&T | 1 | at | North Carolina-Charlotte | 7 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Carolina-Charlotte | 8 | at | North Carolina A&T | 7 | FINAL | Box Score | Recap | Resumption of 3/19 game |
| 4/8/2008 |
| William and Mary |
| at | Norfolk State |
| Canceled | | Recap | CCD, field conditions |
| Missouri Valley Conference |
| 4/8/2008 |
| #5 Wichita State | 4 | at | Kansas State | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Creighton |
| at | South Dakota State |
| Postponed | | Recap | PPD, field conditions |
| 4/8/2008 |
| Evansville | 15 | at | Tennessee-Martin | 10 | FINAL | Box Score | Recap | makeup of 3/4 game |
| 4/8/2008 |
| Illinois |
| at | Bradley |
| Canceled | | Recap | CCD, rain |
| 4/8/2008 |
| Northern Illinois |
| at | Illinois State |
| Canceled | | Recap | CCD, rain |
| 4/8/2008 |
| Southern Illinois | 4 | at | Southeast Missouri State | 11 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Southern Illinois-Edwardsville | 4 | at | Indiana State | 19 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| St. Louis | 3 | at | Missouri State | 7 | FINAL | Box Score | Recap | |
| Mountain West Conference |
| 4/8/2008 |
| #22 Arizona | 11 | at | San Diego State | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas Christian | 4 | at | #30 Baylor | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Colorado Christian | 8 | at | Air Force | 9 | FINAL | Box Score | Recap | 10 innings (makeup of 3/18 game) |
| 4/8/2008 |
| Nevada-Las Vegas | 6 | at | Stephen F. Austin | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| New Mexico | 0 | at | Texas Tech | 10 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Utah | 9 | at | Brigham Young | 7 | FINAL | Box Score | Recap | |
| Northeast Conference |
| 4/8/2008 |
| Brown | 12 | at | Quinnipiac | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Fairfield | 1 | at | Central Connecticut State | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Monmouth | 7 | at | Princeton | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Rider | 6 | at | Long Island | 2 | FINAL | Box Score | Recap | |
| Ohio Valley Conference |
| 4/8/2008 |
| Austin Peay State | 13 | at | Tennessee | 16 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Berea | 2 | at | Tennessee Tech | 16 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Berea | 0 | at | Tennessee Tech | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/8/2008 |
| Evansville | 15 | at | Tennessee-Martin | 10 | FINAL | Box Score | Recap | makeup of 3/4 game |
| 4/8/2008 |
| Illinois College |
| at | Eastern Illinois |
| Postponed | | Recap | PPD, inclement weather |
| 4/8/2008 |
| Marshall | 9 | at | Morehead State | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Southern Illinois | 4 | at | Southeast Missouri State | 11 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Troy | 3 | at | Samford | 4 | FINAL | Box Score | Recap | 11 innings |
| Pac 10 Conference |
| 4/8/2008 |
| #6 UC Irvine | 6 | at | UCLA | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| #15 Cal State Fullerton | 4 | at | Southern California | 5 | FINAL | Box Score | Recap | 11 innings |
| 4/8/2008 |
| #22 Arizona | 11 | at | San Diego State | 6 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Portland | 0 | at | Washington | 3 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Washington State | 8 | at | Gonzaga | 11 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/8/2008 |
| Bucknell | 5 | at | Towson | 14 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Iona | 5 | at | Army | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Lafayette | 5 | vs | Lehigh | 4 | FINAL | Box Score | Recap | Liberty Bell Classic, Philadelphia, PA |
| 4/8/2008 |
| Navy | 7 | at | Maryland-Baltimore County | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Northeastern | 2 | at | Holy Cross | 3 | FINAL | Box Score | Recap | |
| Southeastern Conference |
| 4/8/2008 |
| Louisville | 6 | at | #9 Kentucky | 7 | FINAL | Box Score | Recap | 12 innings |
| 4/8/2008 |
| Western Carolina | 6 | at | #10 South Carolina | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Western Kentucky | 1 | at | #13 Vanderbilt | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| South Alabama | 5 | at | #23 Mississippi | 6 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Winthrop | 5 | at | #24 Georgia | 1 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| North Florida | 3 | at | #29 Florida | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Austin Peay State | 13 | at | Tennessee | 16 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Georgia State | 6 | at | Auburn | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Mississippi State | 8 | at | Memphis | 9 | FINAL | Box Score | Recap | 10 innings |
| 4/8/2008 |
| Mississippi Valley State | 4 | at | Alabama | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Oral Roberts | 9 | at | Arkansas | 4 | FINAL | Box Score | Recap | |
| Southern Conference |
| 4/8/2008 |
| Elon | 2 | at | #4 North Carolina | 0 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Western Carolina | 6 | at | #10 South Carolina | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Appalachian State | 6 | at | South Carolina-Upstate | 4 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Davidson | 4 | at | Virginia Tech | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Gardner-Webb | 10 | at | Furman | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Jacksonville | 6 | at | Georgia Southern | 12 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Savannah State | 1 | at | College of Charleston | 11 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| The Citadel | 7 | at | Charleston Southern | 4 | FINAL | Box Score | Recap | |
| Southland Conference |
| 4/8/2008 |
| Lamar | 5 | at | #7 Rice | 13 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas State | 3 | vs | #11 Texas | 5 | FINAL | Box Score | Recap | 500th win at UT for Augie Garrido (Round Rock, TX) |
| 4/8/2008 |
| Arkansas-Little Rock |
| at | Central Arkansas |
| Postponed | | Recap | PPD to 4/9, inclement weather |
| 4/8/2008 |
| Nevada-Las Vegas | 6 | at | Stephen F. Austin | 5 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Nicholls State | 1 | at | Tulane | 8 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Northwestern State | 2 | at | Louisiana-Lafayette | 9 | FINAL | Box Score | Recap | |
| 4/8/2008 |
| Texas Southern | 5 | at | McNeese State | 9 | FINAL | Box Score | Recap | |