| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/15/2008 |
| #29 Florida | 2 | at | #2 Florida State | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #4 North Carolina | 14 | at | North Carolina-Greensboro | 3 | FINAL | Box Score | Recap | UNC's Tim Fedroff hits for cycle |
| 4/15/2008 |
| #5 UC Irvine | 1 | at | #12 San Diego | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #6 Wichita State | 0 | at | #13 Nebraska | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #7 Rice | 11 | at | #8 Texas A&M | 2 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| South Carolina-Upstate | 4 | at | #9 South Carolina | 14 | FINAL | Box Score | Recap | 3 HR, 9 RBI for SC's Justin Smoak (makeup of 3/19 game) |
| 4/15/2008 |
| #11 Vanderbilt | 8 | at | Lipscomb | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #14 Oklahoma State | 3 | at | Texas-Arlington | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #19 Coastal Carolina | 8 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #17 Kentucky | 9 | at | Cincinnati | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Southern California | 14 | at | #18 Cal State Fullerton | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #20 California | 14 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| East Tennessee State | 8 | at | #21 Georgia | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #22 Arizona | 10 | at | New Mexico | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #23 Mississippi | 5 | vs | Mississippi State | 6 | FINAL | Box Score | Recap | Governor's Cup Game, Pearl, MS |
| 4/15/2008 |
| Pepperdine | 0 | at | #24 Long Beach State | 10 | FINAL | Box Score | Recap | LBSU's Shane Peterson hits for cycle |
| 4/15/2008 |
| #26 East Carolina | 6 | at | North Carolina State | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Eastern Michigan | 3 | at | #27 Michigan | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #28 Georgia Tech |
| at | Georgia Southern |
| Canceled | | Recap | CCD, scheduling conflict |
| 4/15/2008 |
| The Citadel | 6 | at | #30 North Carolina-Wilmington | 16 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/15/2008 |
| Binghamton | 2 | at | Siena | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Dartmouth | 7 | at | Vermont | 8 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| Hartford | 3 | at | Connecticut | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Hofstra | 9 | at | Stony Brook | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Manhattan | 4 | at | Albany | 9 | FINAL | Box Score | Recap | makeup of 4/2 game |
| 4/15/2008 |
| Maryland | 15 | at | Maryland-Baltimore County | 2 | FINAL | Box Score | Recap | |
| Atlantic 10 Conference |
| 4/15/2008 |
| Delaware | 16 | at | Temple | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Duquesne | 0 | at | West Virginia | 14 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Fordham | 8 | at | Rutgers | 8 | FINAL | Box Score | Recap | 11 innings, darkness |
| 4/15/2008 |
| LaSalle | 5 | at | Villanova | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Massachusetts | 4 | vs | Boston College | 3 | FINAL | Box Score | Recap | Beanpot Tournament, Boston, MA |
| 4/15/2008 |
| Rhode Island | 6 | at | Quinnipiac | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Richmond | 5 | at | Virginia Commonwealth | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Tennessee-Martin | 4 | at | St. Louis | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Xavier | 1 | at | Wright State | 5 | FINAL | Box Score | Recap | |
| Atlantic Coast Conference |
| 4/15/2008 |
| #29 Florida | 2 | at | #2 Florida State | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #4 North Carolina | 14 | at | North Carolina-Greensboro | 3 | FINAL | Box Score | Recap | UNC's Tim Fedroff hits for cycle |
| 4/15/2008 |
| #19 Coastal Carolina | 8 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #26 East Carolina | 6 | at | North Carolina State | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #28 Georgia Tech |
| at | Georgia Southern |
| Canceled | | Recap | CCD, scheduling conflict |
| 4/15/2008 |
| Maryland | 15 | at | Maryland-Baltimore County | 2 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Massachusetts | 4 | vs | Boston College | 3 | FINAL | Box Score | Recap | Beanpot Tournament, Boston, MA |
| 4/15/2008 |
| North Carolina Central | 2 | at | Duke | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| North Carolina Central | 0 | at | Duke | 22 | FINAL | Box Score | Recap | No-hitter for Duke (7 innings) |
| 4/15/2008 |
| Wake Forest | 3 | at | Davidson | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Western Carolina | 6 | at | Clemson | 2 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 4/15/2008 |
| South Carolina-Upstate | 4 | at | #9 South Carolina | 14 | FINAL | Box Score | Recap | 3 HR, 9 RBI for SC's Justin Smoak (makeup of 3/19 game) |
| 4/15/2008 |
| #11 Vanderbilt | 8 | at | Lipscomb | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| East Tennessee State | 8 | at | #21 Georgia | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Alabama-Birmingham | 2 | at | Kennesaw State | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Belmont | 7 | at | Austin Peay State | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Jacksonville | 13 | at | Bethune-Cookman | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Mercer | 3 | at | Samford | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| North Carolina A&T | 0 | at | Campbell | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Presbyterian | 1 | at | Gardner-Webb | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| South Florida | 10 | at | Stetson | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| UCF | 3 | at | North Florida | 5 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 4/15/2008 |
| Eastern Michigan | 3 | at | #27 Michigan | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Akron | 5 | at | Penn State | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Illinois | 3 | vs | Eastern Illinois | 13 | FINAL | Box Score | Recap | Mattoon, IL |
| 4/15/2008 |
| Indiana | 4 | at | Louisville | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Northwestern |
| at | Valparaiso |
| Canceled | | Recap | CCD, scheduling conflict |
| 4/15/2008 |
| Purdue | 3 | at | Miami, Ohio | 5 | FINAL | Box Score | Recap | |
| Big 12 Conference |
| 4/15/2008 |
| #6 Wichita State | 0 | at | #13 Nebraska | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #7 Rice | 11 | at | #8 Texas A&M | 2 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #14 Oklahoma State | 3 | at | Texas-Arlington | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Baker | 6 | at | Kansas | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Dallas Baptist | 4 | at | Baylor | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Kansas State | 5 | at | Creighton | 6 | FINAL | Box Score | Recap | 11 innings |
| 4/15/2008 |
| Oklahoma | 5 | at | Texas Christian | 4 | FINAL | Box Score | Recap | 12 innings |
| 4/15/2008 |
| Texas Tech | 8 | at | Nevada-Las Vegas | 9 | FINAL | Box Score | Recap | |
| Big East Conference |
| 4/15/2008 |
| #17 Kentucky | 9 | at | Cincinnati | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Duquesne | 0 | at | West Virginia | 14 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Fordham | 8 | at | Rutgers | 8 | FINAL | Box Score | Recap | 11 innings, darkness |
| 4/15/2008 |
| George Mason | 6 | at | Georgetown | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Hartford | 3 | at | Connecticut | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Indiana | 4 | at | Louisville | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| LaSalle | 5 | at | Villanova | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Pittsburgh | 9 | at | Ohio | 17 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Seton Hall | 8 | at | Princeton | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| South Florida | 10 | at | Stetson | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Toledo | 1 | at | Notre Dame | 6 | FINAL | Box Score | Recap | |
| Big South Conference |
| 4/15/2008 |
| #19 Coastal Carolina | 8 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Elon | 3 | at | High Point | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| James Madison | 4 | at | VMI | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Liberty | 13 | at | William and Mary | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| North Carolina-Asheville | 6 | at | Wofford | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Reinhardt | 8 | at | Charleston Southern | 15 | FINAL | Box Score | Recap | makeup of 2/26 game |
| Big West Conference |
| 4/15/2008 |
| #5 UC Irvine | 1 | at | #12 San Diego | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Southern California | 14 | at | #18 Cal State Fullerton | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #20 California | 14 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Pepperdine | 0 | at | #24 Long Beach State | 10 | FINAL | Box Score | Recap | LBSU's Shane Peterson hits for cycle |
| 4/15/2008 |
| Cal State Northridge | 4 | at | UCLA | 0 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Cal State Sacramento | 7 | at | UC Davis | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Fresno State | 7 | at | Cal Poly | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| UC Riverside | 7 | at | San Diego State | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| UCLA | 22 | at | Cal State Northridge | 2 | FINAL | Box Score | Recap | Resumption of 2/26 game |
| 4/15/2008 |
| Westmont | 3 | at | UC Santa Barbara | 25 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/15/2008 |
| The Citadel | 6 | at | #30 North Carolina-Wilmington | 16 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Delaware | 16 | at | Temple | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Delaware State | 1 | at | Towson | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| George Mason | 6 | at | Georgetown | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Harvard | 6 | vs | Northeastern | 7 | FINAL | Box Score | Recap | 10 innings (Beanpot Tournament, Boston, MA) |
| 4/15/2008 |
| Hofstra | 9 | at | Stony Brook | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| James Madison | 4 | at | VMI | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Liberty | 13 | at | William and Mary | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Longwood | 1 | at | Old Dominion | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Richmond | 5 | at | Virginia Commonwealth | 11 | FINAL | Box Score | Recap | |
| Conference USA |
| 4/15/2008 |
| #7 Rice | 11 | at | #8 Texas A&M | 2 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #26 East Carolina | 6 | at | North Carolina State | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Alabama-Birmingham | 2 | at | Kennesaw State | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Houston | 5 | at | Stephen F. Austin | 0 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Marshall | 9 | at | Eastern Kentucky | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Marshall | 4 | at | Eastern Kentucky | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Memphis | 17 | at | Murray State | 14 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Mississippi Valley State | 0 | at | Southern Mississippi | 11 | FINAL | Box Score | Recap | 400th win at USM for Corky Palmer |
| 4/15/2008 |
| Southeastern Louisiana | 1 | at | Tulane | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| UCF | 3 | at | North Florida | 5 | FINAL | Box Score | Recap | |
| Division I Independents |
| 4/15/2008 |
| Cornell | 3 | at | LeMoyne | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Cornell | 0 | at | LeMoyne | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Dallas Baptist | 4 | at | Baylor | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Longwood | 1 | at | Old Dominion | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Metro State | 10 | at | Northern Colorado | 29 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| New Jersey Tech | 1 | at | Lehigh | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| New York Tech | 18 | at | Long Island | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| North Carolina Central | 2 | at | Duke | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| North Carolina Central | 0 | at | Duke | 22 | FINAL | Box Score | Recap | No-hitter for Duke (7 innings) |
| 4/15/2008 |
| North Park | 15 | at | Chicago State | 14 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| Presbyterian | 1 | at | Gardner-Webb | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Texas-Pan American | 7 | at | Texas State | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Utah Valley State |
| at | Utah |
| Canceled | | Recap | CCD, rain |
| Horizon League |
| 4/15/2008 |
| Bradley | 3 | at | Wisconsin-Milwaukee | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Bradley | 2 | at | Wisconsin-Milwaukee | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Illinois-Chicago | 6 | at | Illinois State | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Kent State | 8 | at | Cleveland State | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Niagara | 3 | at | Youngstown State | 13 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/15/2008 |
| Northwestern |
| at | Valparaiso |
| Canceled | | Recap | CCD, scheduling conflict |
| 4/15/2008 |
| Xavier | 1 | at | Wright State | 5 | FINAL | Box Score | Recap | |
| Ivy League |
| 4/15/2008 |
| Brown | 4 | at | Marist | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Brown | 2 | at | Marist | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Cornell | 3 | at | LeMoyne | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Cornell | 0 | at | LeMoyne | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Dartmouth | 7 | at | Vermont | 8 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| Harvard | 6 | vs | Northeastern | 7 | FINAL | Box Score | Recap | 10 innings (Beanpot Tournament, Boston, MA) |
| 4/15/2008 |
| Seton Hall | 8 | at | Princeton | 4 | FINAL | Box Score | Recap | |
| Metro Atlantic Athletic Conference |
| 4/15/2008 |
| Binghamton | 2 | at | Siena | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Brown | 4 | at | Marist | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Brown | 2 | at | Marist | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Manhattan | 4 | at | Albany | 9 | FINAL | Box Score | Recap | makeup of 4/2 game |
| 4/15/2008 |
| Niagara | 3 | at | Youngstown State | 13 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/15/2008 |
| Rider | 4 | at | Monmouth | 11 | FINAL | Box Score | Recap | |
| Mid American Conference |
| 4/15/2008 |
| Eastern Michigan | 3 | at | #27 Michigan | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Akron | 5 | at | Penn State | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Central Michigan | 7 | at | Oakland | 13 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Grand Valley State | 8 | at | Western Michigan | 15 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Indiana State | 13 | at | Ball State | 14 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| Kent State | 8 | at | Cleveland State | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Pittsburgh | 9 | at | Ohio | 17 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Purdue | 3 | at | Miami, Ohio | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Tiffin | 8 | at | Bowling Green State | 16 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Toledo | 1 | at | Notre Dame | 6 | FINAL | Box Score | Recap | |
| Mid-Eastern Athletic Conference |
| 4/15/2008 |
| Coppin State | 6 | at | Navy | 16 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Delaware State | 1 | at | Towson | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Edward Waters | 4 | at | Florida A&M | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Jacksonville | 13 | at | Bethune-Cookman | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Maryland-Eastern Shore | 0 | at | Mount St. Mary's | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| North Carolina A&T | 0 | at | Campbell | 4 | FINAL | Box Score | Recap | |
| Missouri Valley Conference |
| 4/15/2008 |
| #6 Wichita State | 0 | at | #13 Nebraska | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Bradley | 3 | at | Wisconsin-Milwaukee | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Bradley | 2 | at | Wisconsin-Milwaukee | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Evansville | 3 | at | Western Kentucky | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Illinois-Chicago | 6 | at | Illinois State | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Indiana State | 13 | at | Ball State | 14 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| Kansas State | 5 | at | Creighton | 6 | FINAL | Box Score | Recap | 11 innings |
| 4/15/2008 |
| Missouri State | 9 | at | Arkansas-Little Rock | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| Southeast Missouri State | 4 | at | Southern Illinois | 5 | FINAL | Box Score | Recap | |
| Mountain West Conference |
| 4/15/2008 |
| #22 Arizona | 10 | at | New Mexico | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Oklahoma | 5 | at | Texas Christian | 4 | FINAL | Box Score | Recap | 12 innings |
| 4/15/2008 |
| Southern Utah | 14 | at | Brigham Young | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Texas Tech | 8 | at | Nevada-Las Vegas | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| UC Riverside | 7 | at | San Diego State | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Utah Valley State |
| at | Utah |
| Canceled | | Recap | CCD, rain |
| Northeast Conference |
| 4/15/2008 |
| Central Connecticut State | 3 | at | Holy Cross | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Maryland-Eastern Shore | 0 | at | Mount St. Mary's | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| New York Tech | 18 | at | Long Island | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Rhode Island | 6 | at | Quinnipiac | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Rider | 4 | at | Monmouth | 11 | FINAL | Box Score | Recap | |
| Ohio Valley Conference |
| 4/15/2008 |
| Belmont | 7 | at | Austin Peay State | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Illinois | 3 | vs | Eastern Illinois | 13 | FINAL | Box Score | Recap | Mattoon, IL |
| 4/15/2008 |
| Jacksonville State | 14 | at | Troy | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Marshall | 9 | at | Eastern Kentucky | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Marshall | 4 | at | Eastern Kentucky | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/15/2008 |
| Memphis | 17 | at | Murray State | 14 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Mercer | 3 | at | Samford | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Milligan | 7 | at | Tennessee Tech | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Southeast Missouri State | 4 | at | Southern Illinois | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Tennessee-Martin | 4 | at | St. Louis | 11 | FINAL | Box Score | Recap | |
| Pac 10 Conference |
| 4/15/2008 |
| Southern California | 14 | at | #18 Cal State Fullerton | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #20 California | 14 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #22 Arizona | 10 | at | New Mexico | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Cal State Northridge | 4 | at | UCLA | 0 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Oregon State |
| vs | Portland |
| Suspended | | Recap | Suspended to 5/7, rain (3-0 OSU, bottom 4) Portland, OR |
| 4/15/2008 |
| UCLA | 22 | at | Cal State Northridge | 2 | FINAL | Box Score | Recap | Resumption of 2/26 game |
| 4/15/2008 |
| Washington | 4 | at | Gonzaga | 8 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/15/2008 |
| Central Connecticut State | 3 | at | Holy Cross | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Coppin State | 6 | at | Navy | 16 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| New Jersey Tech | 1 | at | Lehigh | 5 | FINAL | Box Score | Recap | |
| Southeastern Conference |
| 4/15/2008 |
| #29 Florida | 2 | at | #2 Florida State | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| South Carolina-Upstate | 4 | at | #9 South Carolina | 14 | FINAL | Box Score | Recap | 3 HR, 9 RBI for SC's Justin Smoak (makeup of 3/19 game) |
| 4/15/2008 |
| #11 Vanderbilt | 8 | at | Lipscomb | 1 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #17 Kentucky | 9 | at | Cincinnati | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| East Tennessee State | 8 | at | #21 Georgia | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| #23 Mississippi | 5 | vs | Mississippi State | 6 | FINAL | Box Score | Recap | Governor's Cup Game, Pearl, MS |
| 4/15/2008 |
| Arkansas | 2 | at | Oral Roberts | 12 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Nicholls State | 2 | at | Louisiana State | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Tennessee | 6 | at | Middle Tennessee State | 13 | FINAL | Box Score | Recap | |
| Southern Conference |
| 4/15/2008 |
| #4 North Carolina | 14 | at | North Carolina-Greensboro | 3 | FINAL | Box Score | Recap | UNC's Tim Fedroff hits for cycle |
| 4/15/2008 |
| #28 Georgia Tech |
| at | Georgia Southern |
| Canceled | | Recap | CCD, scheduling conflict |
| 4/15/2008 |
| The Citadel | 6 | at | #30 North Carolina-Wilmington | 16 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Elon | 3 | at | High Point | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| North Carolina-Asheville | 6 | at | Wofford | 5 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Wake Forest | 3 | at | Davidson | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Western Carolina | 6 | at | Clemson | 2 | FINAL | Box Score | Recap | |
| Southland Conference |
| 4/15/2008 |
| #14 Oklahoma State | 3 | at | Texas-Arlington | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Houston | 5 | at | Stephen F. Austin | 0 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Louisiana-Lafayette | 2 | at | Northwestern State | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Nicholls State | 2 | at | Louisiana State | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Sam Houston State | 15 | at | Texas Southern | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Southeastern Louisiana | 1 | at | Tulane | 4 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Texas-Pan American | 7 | at | Texas State | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Texas-San Antonio | 3 | at | Lamar | 1 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 4/15/2008 |
| Alabama A&M |
| at | Western Illinois |
| Canceled | | Recap | CCD, travel conflict |
| 4/15/2008 |
| Alabama A&M |
| at | Western Illinois |
| Canceled | | Recap | CCD, travel conflict |
| 4/15/2008 |
| Grambling State |
| at | Alcorn State |
| Postponed | | Recap | PPD, travel conflict |
| 4/15/2008 |
| Mississippi Valley State | 0 | at | Southern Mississippi | 11 | FINAL | Box Score | Recap | 400th win at USM for Corky Palmer |
| 4/15/2008 |
| New Orleans | 7 | at | Jackson State | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Sam Houston State | 15 | at | Texas Southern | 7 | FINAL | Box Score | Recap | |
| Summit League |
| 4/15/2008 |
| Alabama A&M |
| at | Western Illinois |
| Canceled | | Recap | CCD, travel conflict |
| 4/15/2008 |
| Alabama A&M |
| at | Western Illinois |
| Canceled | | Recap | CCD, travel conflict |
| 4/15/2008 |
| Arkansas | 2 | at | Oral Roberts | 12 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Centenary | 2 | at | Louisiana-Monroe | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Central Michigan | 7 | at | Oakland | 13 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Mary (ND) | 11 | at | North Dakota State | 22 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| South Dakota State | 20 | at | Dakota Wesleyan | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Southern Utah | 14 | at | Brigham Young | 10 | FINAL | Box Score | Recap | |
| Sun Belt Conference |
| 4/15/2008 |
| Barry | 10 | at | Florida International | 9 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Centenary | 2 | at | Louisiana-Monroe | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Evansville | 3 | at | Western Kentucky | 11 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Jacksonville State | 14 | at | Troy | 6 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Louisiana-Lafayette | 2 | at | Northwestern State | 3 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Missouri State | 9 | at | Arkansas-Little Rock | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/15/2008 |
| New Orleans | 7 | at | Jackson State | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Tennessee | 6 | at | Middle Tennessee State | 13 | FINAL | Box Score | Recap | |
| West Coast Conference |
| 4/15/2008 |
| #5 UC Irvine | 1 | at | #12 San Diego | 7 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Pepperdine | 0 | at | #24 Long Beach State | 10 | FINAL | Box Score | Recap | LBSU's Shane Peterson hits for cycle |
| 4/15/2008 |
| Oregon State |
| vs | Portland |
| Suspended | | Recap | Suspended to 5/7, rain (3-0 OSU, bottom 4) Portland, OR |
| 4/15/2008 |
| San Francisco State | 6 | at | St. Mary's | 17 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Washington | 4 | at | Gonzaga | 8 | FINAL | Box Score | Recap | |
| Western Athletic Conference |
| 4/15/2008 |
| Cal State Sacramento | 7 | at | UC Davis | 8 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Fresno State | 7 | at | Cal Poly | 10 | FINAL | Box Score | Recap | |
| 4/15/2008 |
| Panhandle State | 4 | at | New Mexico State | 17 | FINAL | Box Score | Recap | 7 innings |