| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/19/2008 | * | #1 Miami, Florida | 5 | at | #2 Florida State | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Oregon State | 12 | at | #3 Arizona State | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Boston College | 0 | at | #4 North Carolina | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | UC Riverside | 5 | at | #5 UC Irvine | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Southern Illinois | 3 | at | #6 Wichita State | 0 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #26 East Carolina | 4 | at | #7 Rice | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 | * | #8 Texas A&M | 11 | at | Baylor | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #23 Mississippi | 5 | at | #9 South Carolina | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #10 Missouri | 6 | at | Oklahoma | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 | * | Auburn | 2 | at | #11 Vanderbilt | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Auburn | 6 | at | #11 Vanderbilt | 3 | FINAL | Box Score | Recap | Resumption of 4/18 game |
| 4/19/2008 | * | St. Mary's | 0 | at | #12 San Diego | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Kansas | 6 | at | #13 Nebraska | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #14 Oklahoma State | 8 | at | #15 Texas | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Wake Forest | 14 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #29 Florida | 13 | at | #17 Kentucky | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #18 Cal State Fullerton | 11 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | North Carolina-Asheville | 4 | at | #19 Coastal Carolina | 10 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Washington | 7 | at | #20 California | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #21 Georgia | 9 | at | Louisiana State | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Washington State | 5 | at | #22 Arizona | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #24 Long Beach State | 9 | at | Cal State Northridge | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #25 Stanford | 6 | at | UCLA | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #27 Michigan | 10 | at | Michigan State | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | #27 Michigan | 7 | at | Michigan State | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | #28 Georgia Tech | 13 | at | Maryland | 14 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #30 North Carolina-Wilmington | 13 | at | Delaware | 5 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/19/2008 | * | Albany | 5 | at | Binghamton | 16 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Albany | 3 | at | Binghamton | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Maine | 11 | at | Maryland-Baltimore County | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Stony Brook | 2 | at | Vermont | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Stony Brook | 2 | at | Vermont | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Hartford | 0 | at | New Jersey Tech | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Hartford | 4 | at | New Jersey Tech | 2 | FINAL | Box Score | Recap | 7 innings |
| Atlantic 10 Conference |
| 4/19/2008 | * | Dayton | 7 | at | George Washington | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Dayton | 7 | at | George Washington | 3 | FINAL | Box Score | Recap | moved from 4/20, impending weather |
| 4/19/2008 | * | Duquesne | 11 | at | Temple | 14 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Fordham | 10 | at | LaSalle | 14 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | North Carolina-Charlotte | 24 | at | Massachusetts | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Rhode Island | 16 | at | Richmond | 12 | FINAL | Box Score | Recap | 12 innings |
| 4/19/2008 | * | Rhode Island | 8 | at | Richmond | 8 | FINAL | Box Score | Recap | 9 innings, darkness |
| 4/19/2008 | * | St. Joseph's | 10 | at | Xavier | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | St. Louis | 10 | at | St. Bonaventure | 14 | FINAL | Box Score | Recap | |
| Atlantic Coast Conference |
| 4/19/2008 | * | #1 Miami, Florida | 5 | at | #2 Florida State | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Boston College | 0 | at | #4 North Carolina | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Wake Forest | 14 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #28 Georgia Tech | 13 | at | Maryland | 14 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Clemson | 1 | at | Duke | 10 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | North Carolina State | 3 | at | Virginia Tech | 4 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 4/19/2008 | * | Belmont | 2 | at | East Tennessee State | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Campbell | 10 | at | Gardner-Webb | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Campbell | 8 | at | Gardner-Webb | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Florida Gulf Coast | 8 | at | Jacksonville | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Lipscomb | 5 | at | South Carolina-Upstate | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Lipscomb | 4 | at | South Carolina-Upstate | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Mercer | 5 | at | Kennesaw State | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Mercer | 4 | at | Kennesaw State | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Stetson | 10 | at | North Florida | 17 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 4/19/2008 | * | #27 Michigan | 10 | at | Michigan State | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | #27 Michigan | 7 | at | Michigan State | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Illinois | 15 | at | Minnesota | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Illinois | 7 | at | Minnesota | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Indiana | 1 | at | Penn State | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Indiana | 2 | at | Penn State | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Northwestern | 13 | at | Iowa | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Northwestern | 3 | at | Iowa | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Purdue | 8 | at | Ohio State | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Purdue |
| at | Ohio State |
| Postponed | | Recap | PPD to 4/20, rain |
| Big 12 Conference |
| 4/19/2008 | * | #8 Texas A&M | 11 | at | Baylor | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #10 Missouri | 6 | at | Oklahoma | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 | * | Kansas | 6 | at | #13 Nebraska | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #14 Oklahoma State | 8 | at | #15 Texas | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Kansas State | 7 | at | Texas Tech | 4 | FINAL | Box Score | Recap | 10 innings |
| Big East Conference |
| 4/19/2008 | * | Georgetown | 7 | at | Cincinnati | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Notre Dame | 6 | at | West Virginia | 11 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Seton Hall | 9 | at | Connecticut | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | South Florida | 6 | at | Rutgers | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | St. John's | 7 | at | Pittsburgh | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Villanova | 1 | at | Louisville | 12 | FINAL | Box Score | Recap | |
| Big South Conference |
| 4/19/2008 | * | North Carolina-Asheville | 4 | at | #19 Coastal Carolina | 10 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Radford | 7 | at | High Point | 11 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | VMI | 6 | at | Liberty | 5 | FINAL | Box Score | Recap | 16 innings |
| 4/19/2008 | * | Winthrop | 5 | at | Charleston Southern | 13 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Winthrop | 21 | at | Charleston Southern | 15 | FINAL | Box Score | Recap | |
| Big West Conference |
| 4/19/2008 | * | UC Riverside | 5 | at | #5 UC Irvine | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #18 Cal State Fullerton | 11 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #24 Long Beach State | 9 | at | Cal State Northridge | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Cal Poly | 10 | at | UC Davis | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| UC Santa Barbara | 23 | at | Southern California | 2 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/19/2008 | * | #30 North Carolina-Wilmington | 13 | at | Delaware | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | James Madison | 5 | at | George Mason | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Old Dominion | 7 | at | Hofstra | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Towson | 4 | at | Northeastern | 8 | FINAL | Box Score | Recap | 11 innings |
| 4/19/2008 | * | Towson | 6 | at | Northeastern | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Virginia Commonwealth | 6 | at | William and Mary | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Virginia Commonwealth | 7 | at | William and Mary | 13 | FINAL | Box Score | Recap | moved from 4/20, impending weather |
| 4/19/2008 |
| North Carolina Central | 4 | at | Georgia State | 12 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| North Carolina Central | 0 | at | Georgia State | 14 | FINAL | Box Score | Recap | 7 innings |
| Conference USA |
| 4/19/2008 | * | #26 East Carolina | 4 | at | #7 Rice | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 | * | Houston | 4 | at | Alabama-Birmingham | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Southern Mississippi | 2 | at | Tulane | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | UCF | 6 | at | Marshall | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Dallas Baptist | 6 | at | Memphis | 4 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 |
| Dallas Baptist | 16 | at | Memphis | 2 | FINAL | Box Score | Recap | 7 innings |
| Division I Independents |
| 4/19/2008 |
| Chicago State | 7 | at | Illinois State | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Dallas Baptist | 6 | at | Memphis | 4 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 |
| Dallas Baptist | 16 | at | Memphis | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Florida Atlantic | 22 | at | New York Tech | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Florida Atlantic | 16 | at | New York Tech | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Hartford | 0 | at | New Jersey Tech | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Hartford | 4 | at | New Jersey Tech | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Hawaii-Hilo | 5 | at | Cal State Sacramento | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Hawaii-Hilo | 1 | at | Cal State Sacramento | 11 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/19/2008 |
| Marist | 3 | at | LeMoyne | 12 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Marist | 5 | at | LeMoyne | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| North Carolina A&T | 7 | at | Longwood | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| North Carolina A&T | 4 | at | Longwood | 2 | FINAL | Box Score | Recap | 11 innings |
| 4/19/2008 |
| North Carolina Central | 4 | at | Georgia State | 12 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| North Carolina Central | 0 | at | Georgia State | 14 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Prairie View A&M | 5 | at | Texas-Pan American | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Prairie View A&M | 3 | at | Texas-Pan American | 8 | FINAL | Box Score | Recap | makeup of 3/10 game |
| 4/19/2008 |
| Presbyterian | 1 | at | Savannah State | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Presbyterian | 6 | at | Savannah State | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Utah Valley State | 17 | vs | Air Force | 6 | FINAL | Box Score | Recap | Northern Colorado Triangular, Greeley, CO |
| 4/19/2008 |
| Utah Valley State | 15 | at | Northern Colorado | 14 | FINAL | Box Score | Recap | Northern Colorado Triangular, Greeley, CO |
| Horizon League |
| 4/19/2008 | * | Butler | 5 | at | Youngstown State | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Butler | 5 | at | Youngstown State | 12 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Wisconsin-Milwaukee | 4 | at | Cleveland State | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Wisconsin-Milwaukee | 4 | at | Cleveland State | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Wright State |
| at | Valparaiso |
| Canceled | | Recap | CCD, rain |
| 4/19/2008 | * | Wright State |
| at | Valparaiso |
| Canceled | | Recap | CCD, rain |
| Ivy League |
| 4/19/2008 | * | Brown | 4 | at | Harvard | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Brown | 3 | at | Harvard | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Columbia | 7 | at | Cornell | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Columbia | 8 | at | Cornell | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Pennsylvania | 0 | at | Princeton | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Pennsylvania | 2 | at | Princeton | 5 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Yale | 5 | at | Dartmouth | 3 | FINAL | Box Score | Recap | 8 innings |
| 4/19/2008 | * | Yale | 6 | at | Dartmouth | 13 | FINAL | Box Score | Recap | |
| Metro Atlantic Athletic Conference |
| 4/19/2008 | * | Iona | 0 | at | Manhattan | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Iona | 0 | at | Manhattan | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Rider | 17 | at | Fairfield | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Rider | 12 | at | Fairfield | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Siena | 12 | at | Canisius | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Siena | 3 | at | Canisius | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | St. Peter's | 10 | at | Niagara | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | St. Peter's | 0 | at | Niagara | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| Marist | 3 | at | LeMoyne | 12 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Marist | 5 | at | LeMoyne | 6 | FINAL | Box Score | Recap | 7 innings |
| Mid American Conference |
| 4/19/2008 | * | Ball State | 6 | at | Central Michigan | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Kent State | 15 | at | Bowling Green State | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Miami, Ohio | 0 | at | Buffalo | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Northern Illinois | 5 | at | Toledo | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Ohio | 0 | at | Akron | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Western Michigan | 9 | at | Eastern Michigan | 12 | FINAL | Box Score | Recap | |
| Mid-Eastern Athletic Conference |
| 4/19/2008 | * | Bethune-Cookman | 9 | at | Coppin State | 1 | FINAL | Box Score | | |
| 4/19/2008 | * | Bethune-Cookman | 16 | at | Coppin State | 2 | FINAL | Box Score | | 5 innings, run rule |
| 4/19/2008 | * | Maryland-Eastern Shore | 1 | at | Florida A&M | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Maryland-Eastern Shore | 7 | at | Florida A&M | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Norfolk State | 5 | at | Delaware State | 11 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Norfolk State | 2 | at | Delaware State | 4 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 |
| North Carolina A&T | 7 | at | Longwood | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| North Carolina A&T | 4 | at | Longwood | 2 | FINAL | Box Score | Recap | 11 innings |
| Missouri Valley Conference |
| 4/19/2008 | * | Southern Illinois | 3 | at | #6 Wichita State | 0 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Creighton | 3 | at | Northern Iowa | 2 | FINAL | Box Score | Recap | makeup 4/18 game |
| 4/19/2008 | * | Creighton | 2 | at | Northern Iowa | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Indiana State | 4 | at | Evansville | 6 | FINAL | Box Score | Recap | Resumption of 4/18 game |
| 4/19/2008 | * | Indiana State | 14 | at | Evansville | 13 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Missouri State | 12 | at | Bradley | 2 | FINAL | Box Score | Recap | 8 innings, run rule (makeup of 4/18 game) |
| 4/19/2008 | * | Missouri State | 6 | at | Bradley | 9 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Chicago State | 7 | at | Illinois State | 6 | FINAL | Box Score | Recap | |
| Mountain West Conference |
| 4/19/2008 | * | San Diego State | 18 | at | Nevada-Las Vegas | 19 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 | * | Texas Christian | 11 | at | Brigham Young | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Utah | 3 | at | New Mexico | 13 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| Utah Valley State | 17 | vs | Air Force | 6 | FINAL | Box Score | Recap | Northern Colorado Triangular, Greeley, CO |
| Northeast Conference |
| 4/19/2008 | * | Long Island | 6 | at | Central Connecticut State | 0 | FINAL | Box Score | Recap | 7 innings (New Britain, CT) |
| 4/19/2008 | * | Long Island | 3 | at | Central Connecticut State | 16 | FINAL | Box Score | Recap | 7 innings (New Britain, CT) |
| 4/19/2008 | * | Mount St. Mary's | 1 | at | Sacred Heart | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Mount St. Mary's | 3 | at | Sacred Heart | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Quinnipiac | 3 | at | Monmouth | 10 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Quinnipiac | 1 | at | Monmouth | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Wagner | 2 | at | Fairleigh Dickinson | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Wagner | 13 | at | Fairleigh Dickinson | 4 | FINAL | Box Score | Recap | 7 innings |
| Ohio Valley Conference |
| 4/19/2008 | * | Jacksonville State | 2 | at | Eastern Illinois | 19 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Jacksonville State |
| at | Eastern Illinois |
| Postponed | | Recap | PPD to 4/20, rain |
| 4/19/2008 | * | Murray State | 6 | at | Eastern Kentucky | 0 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Murray State | 7 | at | Eastern Kentucky | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Samford | 11 | at | Southeast Missouri State | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Samford | 10 | at | Southeast Missouri State | 11 | FINAL | Box Score | Recap | 8 innings |
| 4/19/2008 | * | Tennessee Tech | 5 | at | Austin Peay State | 10 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Tennessee Tech | 7 | at | Austin Peay State | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Tennessee-Martin | 8 | at | Morehead State | 16 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Tennessee-Martin | 16 | at | Morehead State | 12 | FINAL | Box Score | Recap | 7 innings |
| Pac 10 Conference |
| 4/19/2008 | * | Oregon State | 12 | at | #3 Arizona State | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Washington | 7 | at | #20 California | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Washington State | 5 | at | #22 Arizona | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #25 Stanford | 6 | at | UCLA | 1 | FINAL | Box Score | Recap | |
| 4/19/2008 |
| UC Santa Barbara | 23 | at | Southern California | 2 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/19/2008 | * | Lafayette | 1 | at | Holy Cross | 2 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Lafayette | 1 | at | Holy Cross | 6 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Lehigh | 4 | at | Army | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Lehigh | 4 | at | Army | 13 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Navy | 4 | at | Bucknell | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Navy | 16 | at | Bucknell | 6 | FINAL | Box Score | Recap | |
| Southeastern Conference |
| 4/19/2008 | * | #23 Mississippi | 5 | at | #9 South Carolina | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Auburn | 2 | at | #11 Vanderbilt | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Auburn | 6 | at | #11 Vanderbilt | 3 | FINAL | Box Score | Recap | Resumption of 4/18 game |
| 4/19/2008 | * | #29 Florida | 13 | at | #17 Kentucky | 7 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | #21 Georgia | 9 | at | Louisiana State | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Mississippi State | 7 | at | Alabama | 21 | FINAL | Box Score | Recap | makeup of 4/18 game |
| 4/19/2008 | * | Mississippi State | 6 | at | Alabama | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Tennessee | 4 | at | Arkansas | 5 | FINAL | Box Score | Recap | 10 innings |
| Southern Conference |
| 4/19/2008 | * | Elon | 1 | at | College of Charleston | 17 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Georgia Southern | 20 | at | Davidson | 2 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | North Carolina-Greensboro | 9 | at | The Citadel | 3 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Western Carolina |
| at | Appalachian State |
| Postponed | | Recap | PPD to 4/20, rain |
| 4/19/2008 | * | Wofford | 5 | at | Furman | 6 | FINAL | Box Score | Recap | 10 innings |
| Southland Conference |
| 4/19/2008 | * | Central Arkansas | 6 | at | Texas State | 16 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/19/2008 | * | Lamar | 12 | at | Texas A&M-Corpus Christi | 14 | FINAL | Box Score | Recap | 10 innings |
| 4/19/2008 | * | McNeese State | 2 | at | Sam Houston State | 10 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Northwestern State | 15 | at | Nicholls State | 1 | FINAL | Box Score | Recap | 7 innings, run rule (makeup of 4/18 game) |
| 4/19/2008 | * | Northwestern State | 9 | at | Nicholls State | 4 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Southeastern Louisiana | 5 | at | Texas-Arlington | 8 | FINAL | Box Score | Recap | |
| 4/19/2008 | * | Stephen F. Austin | 10 | at | Texas-San Antonio | 12 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 4/19/2008 | * | Alabama State | 7 | at | Alabama A&M | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Alabama State | 4 | at | Alabama A&M | 1 | FINAL | Box Score | Recap | 7 innings |
| 4/19/2008 | * | Grambling State | 9 | at | |