| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/20/2008 | * | #1 Miami, Florida | 11 | at | #2 Florida State | 10 | FINAL | Box Score | Recap | 7 innings, travel curfew |
| 4/20/2008 | * | Oregon State | 12 | at | #3 Arizona State | 15 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Boston College | 2 | at | #4 North Carolina | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | UC Riverside | 7 | at | #5 UC Irvine | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Southern Illinois | 3 | at | #6 Wichita State | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #26 East Carolina | 1 | at | #7 Rice | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #8 Texas A&M | 13 | at | Baylor | 12 | FINAL | Box Score | Recap | 11 innings |
| 4/20/2008 | * | #23 Mississippi | 1 | at | #9 South Carolina | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #10 Missouri | 4 | at | Oklahoma | 22 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/20/2008 | * | Auburn | 5 | at | #11 Vanderbilt | 9 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | St. Mary's | 1 | at | #12 San Diego | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Kansas | 6 | at | #13 Nebraska | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #14 Oklahoma State | 13 | at | #15 Texas | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Wake Forest | 2 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | 11 innings |
| 4/20/2008 | * | #29 Florida | 2 | at | #17 Kentucky | 3 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 | * | #18 Cal State Fullerton | 2 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | North Carolina-Asheville | 2 | at | #19 Coastal Carolina | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Washington | 4 | at | #20 California | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #21 Georgia | 10 | at | Louisiana State | 10 | FINAL | Box Score | Recap | 12 innings, travel curfew |
| 4/20/2008 | * | Washington State | 2 | at | #22 Arizona | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #24 Long Beach State | 4 | at | Cal State Northridge | 1 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #25 Stanford | 2 | at | UCLA | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Michigan State | 6 | at | #27 Michigan | 27 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #28 Georgia Tech | 9 | at | Maryland | 6 | FINAL | Box Score | Recap | 5 innings, rain |
| 4/20/2008 | * | #30 North Carolina-Wilmington | 17 | at | Delaware | 7 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/20/2008 | * | Albany | 10 | at | Binghamton | 13 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Maine | 2 | at | Maryland-Baltimore County | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Stony Brook | 15 | at | Vermont | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Hartford | 5 | at | New Jersey Tech | 3 | FINAL | Box Score | Recap | |
| Atlantic 10 Conference |
| 4/20/2008 | * | Duquesne | 7 | at | Temple | 9 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Fordham | 2 | at | LaSalle | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | North Carolina-Charlotte | 8 | at | Massachusetts | 12 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | St. Joseph's | 3 | at | Xavier | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | St. Louis | 2 | at | St. Bonaventure | 4 | FINAL | Box Score | Recap | |
| Atlantic Coast Conference |
| 4/20/2008 | * | #1 Miami, Florida | 11 | at | #2 Florida State | 10 | FINAL | Box Score | Recap | 7 innings, travel curfew |
| 4/20/2008 | * | Boston College | 2 | at | #4 North Carolina | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Wake Forest | 2 | at | #16 Virginia | 3 | FINAL | Box Score | Recap | 11 innings |
| 4/20/2008 | * | #28 Georgia Tech | 9 | at | Maryland | 6 | FINAL | Box Score | Recap | 5 innings, rain |
| 4/20/2008 | * | Clemson | 6 | at | Duke | 6 | FINAL | Box Score | Recap | 11 innings, rain |
| 4/20/2008 | * | North Carolina State | 11 | at | Virginia Tech | 5 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 4/20/2008 | * | Belmont | 17 | at | East Tennessee State | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Stetson | 13 | at | North Florida | 4 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 4/20/2008 | * | Michigan State | 6 | at | #27 Michigan | 27 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Illinois | 3 | at | Minnesota | 4 | FINAL | Box Score | Recap | 7 innings (makeup of 4/18 game) |
| 4/20/2008 | * | Illinois | 9 | at | Minnesota | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Indiana | 9 | at | Penn State | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Northwestern | 13 | at | Iowa | 6 | FINAL | Box Score | Recap | 7 innings (makeup of 4/18 game) |
| 4/20/2008 | * | Northwestern | 9 | at | Iowa | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Purdue | 4 | at | Ohio State | 8 | FINAL | Box Score | Recap | 7 innings (makeup of 4/19 game) |
| 4/20/2008 | * | Purdue | 7 | at | Ohio State | 5 | FINAL | Box Score | Recap | |
| Big 12 Conference |
| 4/20/2008 | * | #8 Texas A&M | 13 | at | Baylor | 12 | FINAL | Box Score | Recap | 11 innings |
| 4/20/2008 | * | #10 Missouri | 4 | at | Oklahoma | 22 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/20/2008 | * | Kansas | 6 | at | #13 Nebraska | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #14 Oklahoma State | 13 | at | #15 Texas | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Kansas State | 4 | at | Texas Tech | 19 | FINAL | Box Score | Recap | 7 innings, run rule |
| Big East Conference |
| 4/20/2008 | * | Georgetown | 8 | at | Cincinnati | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Notre Dame | 9 | at | West Virginia | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Seton Hall | 5 | at | Connecticut | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | South Florida | 4 | at | Rutgers | 5 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 | * | St. John's | 11 | at | Pittsburgh | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Villanova | 3 | at | Louisville | 1 | FINAL | Box Score | Recap | |
| Big South Conference |
| 4/20/2008 | * | North Carolina-Asheville | 2 | at | #19 Coastal Carolina | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Radford | 7 | at | High Point | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | VMI | 1 | at | Liberty | 6 | FINAL | Box Score | Recap | |
| Big West Conference |
| 4/20/2008 | * | UC Riverside | 7 | at | #5 UC Irvine | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #18 Cal State Fullerton | 2 | at | Pacific | 1 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #24 Long Beach State | 4 | at | Cal State Northridge | 1 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Cal Poly | 4 | at | UC Davis | 2 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Southern California | 0 | at | UC Santa Barbara | 6 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/20/2008 | * | #30 North Carolina-Wilmington | 17 | at | Delaware | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | James Madison |
| at | George Mason |
| Canceled | | Recap | CCD, rain |
| 4/20/2008 | * | Old Dominion | 4 | at | Hofstra | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Towson | 1 | at | Northeastern | 2 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| North Carolina Central | 7 | at | Georgia State | 9 | FINAL | Box Score | Recap | |
| Conference USA |
| 4/20/2008 | * | #26 East Carolina | 1 | at | #7 Rice | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Houston | 10 | at | Alabama-Birmingham | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Southern Mississippi | 10 | at | Tulane | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | UCF | 9 | at | Marshall | 12 | FINAL | Box Score | Recap | |
| Division I Independents |
| 4/20/2008 |
| Air Force | 13 | at | Northern Colorado | 12 | FINAL | Box Score | Recap | Northern Colorado Triangular, Greeley, CO |
| 4/20/2008 |
| Chicago State | 1 | at | Illinois State | 13 | FINAL | Box Score | Recap | 7 innings, run rule (makeup of 4/18 game) |
| 4/20/2008 |
| Chicago State | 5 | at | Illinois State | 15 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 |
| Florida Atlantic | 0 | at | New York Tech | 2 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Hartford | 5 | at | New Jersey Tech | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Hawaii-Hilo | 2 | at | Cal State Sacramento | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Marist | 7 | at | LeMoyne | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| North Carolina A&T | 13 | at | Longwood | 12 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 |
| North Carolina Central | 7 | at | Georgia State | 9 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Prairie View A&M | 5 | at | Texas-Pan American | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Presbyterian | 3 | at | Savannah State | 13 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Utah Valley State | 11 | at | Northern Colorado | 13 | FINAL | Box Score | Recap | Northern Colorado Triangular, Greeley, CO |
| Horizon League |
| 4/20/2008 | * | Butler | 9 | at | Cleveland State | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Butler | 1 | at | Cleveland State | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Wisconsin-Milwaukee | 9 | at | Youngstown State | 10 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 | * | Wisconsin-Milwaukee | 3 | at | Youngstown State | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Wright State | 20 | at | Illinois-Chicago | 0 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Wright State | 6 | at | Illinois-Chicago | 1 | FINAL | Box Score | Recap | |
| Ivy League |
| 4/20/2008 | * | Brown | 3 | at | Harvard | 9 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Brown | 2 | at | Harvard | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Columbia | 7 | at | Cornell | 11 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Columbia | 6 | at | Cornell | 2 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Pennsylvania | 10 | at | Princeton | 7 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Pennsylvania | 5 | at | Princeton | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Yale | 8 | at | Dartmouth | 7 | FINAL | Box Score | Recap | 11 innings |
| 4/20/2008 | * | Yale | 2 | at | Dartmouth | 7 | FINAL | Box Score | Recap | |
| Metro Atlantic Athletic Conference |
| 4/20/2008 | * | Iona | 1 | at | Manhattan | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Rider | 11 | at | Fairfield | 12 | FINAL | Box Score | Recap | 12 innings |
| 4/20/2008 | * | Siena | 9 | at | Canisius | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | St. Peter's | 4 | at | Niagara | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Marist | 7 | at | LeMoyne | 11 | FINAL | Box Score | Recap | |
| Mid American Conference |
| 4/20/2008 | * | Ball State | 4 | at | Central Michigan | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Kent State | 6 | at | Bowling Green State | 1 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Miami, Ohio | 10 | at | Buffalo | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Northern Illinois | 2 | at | Toledo | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Ohio | 3 | at | Akron | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Western Michigan | 5 | at | Eastern Michigan | 6 | FINAL | Box Score | Recap | |
| Mid-Eastern Athletic Conference |
| 4/20/2008 | * | Bethune-Cookman | 18 | at | Coppin State | 7 | FINAL | Box Score | | 7 innings |
| 4/20/2008 | * | Maryland-Eastern Shore | 4 | at | Florida A&M | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Norfolk State | 6 | at | Delaware State | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| North Carolina A&T | 13 | at | Longwood | 12 | FINAL | Box Score | Recap | 10 innings |
| Missouri Valley Conference |
| 4/20/2008 | * | Southern Illinois | 3 | at | #6 Wichita State | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Creighton | 7 | at | Northern Iowa | 9 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Indiana State | 5 | at | Evansville | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Missouri State | 12 | at | Bradley | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Chicago State | 1 | at | Illinois State | 13 | FINAL | Box Score | Recap | 7 innings, run rule (makeup of 4/18 game) |
| 4/20/2008 |
| Chicago State | 5 | at | Illinois State | 15 | FINAL | Box Score | Recap | 7 innings |
| Mountain West Conference |
| 4/20/2008 | * | San Diego State | 16 | at | Nevada-Las Vegas | 20 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Utah | 8 | at | New Mexico | 15 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Air Force | 13 | at | Northern Colorado | 12 | FINAL | Box Score | Recap | Northern Colorado Triangular, Greeley, CO |
| Northeast Conference |
| 4/20/2008 | * | Long Island | 3 | at | Central Connecticut State | 19 | FINAL | Box Score | Recap | New Britain, CT |
| 4/20/2008 | * | Mount St. Mary's | 8 | at | Sacred Heart | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Quinnipiac | 1 | at | Monmouth | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Wagner | 0 | at | Fairleigh Dickinson | 4 | FINAL | Box Score | Recap | |
| Ohio Valley Conference |
| 4/20/2008 | * | Jacksonville State | 2 | at | Eastern Illinois | 0 | FINAL | Box Score | Recap | makeup of 4/19 game |
| 4/20/2008 | * | Jacksonville State | 6 | at | Eastern Illinois | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Murray State | 4 | at | Eastern Kentucky | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Samford | 6 | at | Southeast Missouri State | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Tennessee Tech | 3 | at | Austin Peay State | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Tennessee-Martin | 8 | at | Morehead State | 13 | FINAL | Box Score | Recap | |
| Pac 10 Conference |
| 4/20/2008 | * | Oregon State | 12 | at | #3 Arizona State | 15 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Washington | 4 | at | #20 California | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Washington State | 2 | at | #22 Arizona | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #25 Stanford | 2 | at | UCLA | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Southern California | 0 | at | UC Santa Barbara | 6 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/20/2008 | * | Lafayette | 5 | at | Holy Cross | 12 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Lafayette | 6 | at | Holy Cross | 3 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Lehigh | 0 | at | Army | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Lehigh | 0 | at | Army | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Navy | 2 | at | Bucknell | 8 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Navy |
| at | Bucknell |
| Postponed | | Recap | PPD to 4/21, rain |
| Southeastern Conference |
| 4/20/2008 | * | #23 Mississippi | 1 | at | #9 South Carolina | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Auburn | 5 | at | #11 Vanderbilt | 9 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | #29 Florida | 2 | at | #17 Kentucky | 3 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 | * | #21 Georgia | 10 | at | Louisiana State | 10 | FINAL | Box Score | Recap | 12 innings, travel curfew |
| 4/20/2008 | * | Mississippi State | 3 | at | Alabama | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Tennessee | 7 | at | Arkansas | 6 | FINAL | Box Score | Recap | 10 innings |
| Southern Conference |
| 4/20/2008 | * | Elon | 6 | at | College of Charleston | 13 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Georgia Southern | 6 | at | Davidson | 7 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | North Carolina-Greensboro | 7 | at | The Citadel | 8 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Western Carolina | 8 | at | Appalachian State | 12 | FINAL | Box Score | Recap | makeup of 4/19 game |
| 4/20/2008 | * | Western Carolina | 5 | at | Appalachian State | 4 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 | * | Wofford | 9 | at | Furman | 13 | FINAL | Box Score | Recap | |
| Southland Conference |
| 4/20/2008 | * | Central Arkansas | 5 | at | Texas State | 11 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Lamar | 8 | at | Texas A&M-Corpus Christi | 5 | FINAL | Box Score | Recap | 12 innings |
| 4/20/2008 | * | McNeese State | 1 | at | Sam Houston State | 11 | FINAL | Box Score | Recap | 8 innings, run rule |
| 4/20/2008 | * | Northwestern State | 4 | at | Nicholls State | 3 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Southeastern Louisiana | 6 | at | Texas-Arlington | 2 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Stephen F. Austin | 0 | at | Texas-San Antonio | 7 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 4/20/2008 | * | Alabama State | 8 | at | Alabama A&M | 7 | FINAL | Box Score | Recap | 10 innings |
| 4/20/2008 | * | Grambling State | 6 | at | Arkansas-Pine Bluff | 10 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Jackson State | 2 | at | Mississippi Valley State | 0 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Jackson State | 11 | at | Mississippi Valley State | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/20/2008 | * | Southern | 17 | at | Texas Southern | 3 | FINAL | Box Score | | |
| 4/20/2008 |
| Prairie View A&M | 5 | at | Texas-Pan American | 11 | FINAL | Box Score | Recap | |
| Summit League |
| 4/20/2008 | * | Centenary | 14 | at | Oakland | 2 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | North Dakota State | 5 | at | IUPU-Fort Wayne | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Western Illinois | 4 | at | Oral Roberts | 10 | FINAL | Box Score | Recap | |
| Sun Belt Conference |
| 4/20/2008 | * | Arkansas State | 5 | at | Western Kentucky | 13 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Arkansas-Little Rock | 3 | at | Troy | 15 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/20/2008 | * | Florida International | 7 | at | New Orleans | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Louisiana-Lafayette | 8 | at | South Alabama | 6 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Middle Tennessee State | 8 | at | Louisiana-Monroe | 16 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Florida Atlantic | 0 | at | New York Tech | 2 | FINAL | Box Score | Recap | |
| West Coast Conference |
| 4/20/2008 | * | St. Mary's | 1 | at | #12 San Diego | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Pepperdine | 10 | at | Loyola Marymount | 1 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Portland | 1 | at | Gonzaga | 5 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | San Francisco | 6 | at | Santa Clara | 7 | FINAL | Box Score | Recap | |
| Western Athletic Conference |
| 4/20/2008 | * | Fresno State | 24 | at | New Mexico State | 6 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/20/2008 | * | Louisiana Tech | 2 | at | San Jose State | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 | * | Nevada | 0 | at | Hawaii | 4 | FINAL | Box Score | Recap | |
| 4/20/2008 |
| Hawaii-Hilo | 2 | at | Cal State Sacramento | 8 | FINAL | Box Score | Recap | |