| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
| National Collegiate Baseball Writers Poll |
| 4/29/2008 |
| #3 Florida State | 13 | at | Stetson | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #6 Texas A&M | 3 | at | Texas Christian | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Loyola Marymount | 11 | at | #7 UC Irvine | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #8 San Diego | 3 | at | #19 Cal State Fullerton | 12 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Western Illinois | 4 | at | #9 Nebraska | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Kansas State | 3 | at | #11 Wichita State | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Kansas | 3 | vs | #14 Missouri | 0 | FINAL | Box Score | Recap | Kansas City, MO |
| 4/29/2008 |
| San Diego State | 2 | at | #20 Arizona | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #30 East Carolina | 14 | at | #24 North Carolina-Wilmington | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #25 Oregon State | 6 | at | Gonzaga | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Texas State | 0 | at | #26 Texas | 11 | FINAL | Box Score | Recap | No-hitter for UT's Kenn Kasparek |
| 4/29/2008 |
| Mount St. Mary's | 1 | at | #27 Virginia | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Western Michigan | 4 | at | #28 Michigan | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| New Orleans | 9 | at | #29 Southern Mississippi | 3 | FINAL | Box Score | Recap | |
| America East Conference |
| 4/29/2008 |
| Dartmouth |
| at | Hartford |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Marist |
| at | Albany |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Stony Brook |
| at | Iona |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Towson |
| at | Maryland-Baltimore County |
| Canceled | | Recap | CCD, field conditions |
| 4/29/2008 |
| Vermont |
| at | Connecticut |
| Canceled | | Recap | CCD, inclement weather |
| Atlantic 10 Conference |
| 4/29/2008 |
| Buffalo | 4 | at | St. Bonaventure | 9 | FINAL | Box Score | Recap | Big Four Classic, Olean, NY |
| 4/29/2008 |
| Cincinnati | 13 | at | Xavier | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| George Washington |
| at | Maryland-Eastern Shore |
| Postponed | | Recap | PPD to 4/30, inclement weather |
| 4/29/2008 |
| Harris-Stowe | 1 | at | St. Louis | 12 | FINAL | Box Score | Recap | 7 innings, run rule |
| 4/29/2008 |
| Hofstra | 9 | at | Fordham | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Holy Cross |
| at | Rhode Island |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| North Carolina-Charlotte | 7 | at | Winthrop | 5 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Siena |
| at | Massachusetts |
| Canceled | | Recap | CCD, inclement weather |
| Atlantic Coast Conference |
| 4/29/2008 |
| #3 Florida State | 13 | at | Stetson | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Mount St. Mary's | 1 | at | #27 Virginia | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Maryland |
| at | West Virginia |
| Postponed | | Recap | PPD, inclement weather |
| 4/29/2008 |
| Quinnipiac |
| at | Boston College |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Wake Forest | 11 | at | North Carolina-Greensboro | 6 | FINAL | Box Score | Recap | |
| Atlantic Sun Conference |
| 4/29/2008 |
| #3 Florida State | 13 | at | Stetson | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Belmont | 5 | at | Tennessee-Martin | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/29/2008 |
| Belmont | 14 | at | Tennessee-Martin | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/29/2008 |
| Bethune-Cookman | 3 | at | Jacksonville | 1 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Florida Gulf Coast |
| at | Florida |
| Postponed | | Recap | PPD, scheduling conflict |
| 4/29/2008 |
| North Carolina Central | 1 | at | East Tennessee State | 13 | FINAL | Box Score | Recap | |
| Big 10 Conference |
| 4/29/2008 |
| Western Michigan | 4 | at | #28 Michigan | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Southern Illinois | 3 | at | Illinois | 2 | FINAL | Box Score | Recap | 11 innings |
| Big 12 Conference |
| 4/29/2008 |
| #6 Texas A&M | 3 | at | Texas Christian | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Western Illinois | 4 | at | #9 Nebraska | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Kansas State | 3 | at | #11 Wichita State | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Kansas | 3 | vs | #14 Missouri | 0 | FINAL | Box Score | Recap | Kansas City, MO |
| 4/29/2008 |
| Texas State | 0 | at | #26 Texas | 11 | FINAL | Box Score | Recap | No-hitter for UT's Kenn Kasparek |
| 4/29/2008 |
| Baylor | 14 | at | Texas-Arlington | 4 | FINAL | Box Score | Recap | |
| Big East Conference |
| 4/29/2008 |
| Cincinnati | 13 | at | Xavier | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Georgetown | 9 | at | George Mason | 13 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Maryland |
| at | West Virginia |
| Postponed | | Recap | PPD, inclement weather |
| 4/29/2008 |
| Mississippi Valley State | 0 | at | Notre Dame | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Morehead State | 0 | at | Louisville | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| New York Tech |
| at | St. John's |
| Postponed | | Recap | PPD, inclement weather |
| 4/29/2008 |
| Pittsburgh | 2 | at | Kent State | 9 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Rutgers | 5 | at | Delaware | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| UCF | 6 | at | South Florida | 14 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Vermont |
| at | Connecticut |
| Canceled | | Recap | CCD, inclement weather |
| Big South Conference |
| 4/29/2008 |
| North Carolina-Charlotte | 7 | at | Winthrop | 5 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| VMI |
| at | Virginia Commonwealth |
| Canceled | | Recap | CCD, field conditions |
| Big West Conference |
| 4/29/2008 |
| Loyola Marymount | 11 | at | #7 UC Irvine | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #8 San Diego | 3 | at | #19 Cal State Fullerton | 12 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Nevada-Las Vegas | 1 | at | Cal State Northridge | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| San Francisco | 6 | at | Pacific | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Southern California | 4 | at | Cal Poly | 3 | FINAL | Box Score | Recap | |
| Colonial Athletic Association |
| 4/29/2008 |
| #30 East Carolina | 14 | at | #24 North Carolina-Wilmington | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Bryant | 3 | at | Northeastern | 5 | FINAL | Box Score | Recap | makeup of 4/28 game |
| 4/29/2008 |
| Georgetown | 9 | at | George Mason | 13 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Hofstra | 9 | at | Fordham | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Rutgers | 5 | at | Delaware | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Towson |
| at | Maryland-Baltimore County |
| Canceled | | Recap | CCD, field conditions |
| 4/29/2008 |
| VMI |
| at | Virginia Commonwealth |
| Canceled | | Recap | CCD, field conditions |
| Conference USA |
| 4/29/2008 |
| #30 East Carolina | 14 | at | #24 North Carolina-Wilmington | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| New Orleans | 9 | at | #29 Southern Mississippi | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Houston | 3 | at | Lamar | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Marshall | 10 | at | Ohio | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Mississippi | 10 | at | Memphis | 1 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Nicholls State | 3 | at | Tulane | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| UCF | 6 | at | South Florida | 14 | FINAL | Box Score | Recap | |
| Division I Independents |
| 4/29/2008 |
| Brigham Young | 17 | at | Northern Colorado | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Chicago State | 9 | at | North Park | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Dallas Baptist | 8 | at | Sam Houston State | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| New Jersey Tech | 10 | at | St. Peter's | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| New York Tech |
| at | St. John's |
| Postponed | | Recap | PPD, inclement weather |
| 4/29/2008 |
| North Carolina Central | 1 | at | East Tennessee State | 13 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Northwest Nazarene | 4 | at | Utah Valley State | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Northwest Nazarene | 6 | at | Utah Valley State | 15 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Texas-Pan American | 9 | at | Stephen F. Austin | 10 | FINAL | Box Score | Recap | |
| Horizon League |
| 4/29/2008 |
| Butler | 7 | at | Indianapolis | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Cleveland State | 12 | at | Akron | 9 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Northern Illinois | 5 | at | Wisconsin-Milwaukee | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Valparaiso | 3 | at | Bradley | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/29/2008 |
| Valparaiso | 1 | at | Bradley | 2 | FINAL | Box Score | Recap | 7 innings |
| Ivy League |
| 4/29/2008 |
| Dartmouth |
| at | Hartford |
| Canceled | | Recap | CCD, inclement weather |
| Metro Atlantic Athletic Conference |
| 4/29/2008 |
| Marist |
| at | Albany |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| New Jersey Tech | 10 | at | St. Peter's | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Niagara | 9 | at | Canisius | 6 | FINAL | Box Score | Recap | Big Four Classic, Buffalo, NY |
| 4/29/2008 |
| Sacred Heart |
| at | Fairfield |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Siena |
| at | Massachusetts |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Stony Brook |
| at | Iona |
| Canceled | | Recap | CCD, inclement weather |
| Mid American Conference |
| 4/29/2008 |
| Western Michigan | 4 | at | #28 Michigan | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Buffalo | 4 | at | St. Bonaventure | 9 | FINAL | Box Score | Recap | Big Four Classic, Olean, NY |
| 4/29/2008 |
| Cleveland State | 12 | at | Akron | 9 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Indiana Tech | 7 | at | Eastern Michigan | 9 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Marshall | 10 | at | Ohio | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Miami, Ohio | 7 | at | Eastern Kentucky | 9 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Northern Illinois | 5 | at | Wisconsin-Milwaukee | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Pittsburgh | 2 | at | Kent State | 9 | FINAL | Box Score | Recap | |
| Mid-Eastern Athletic Conference |
| 4/29/2008 |
| Bethune-Cookman | 3 | at | Jacksonville | 1 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| George Washington |
| at | Maryland-Eastern Shore |
| Postponed | | Recap | PPD to 4/30, inclement weather |
| 4/29/2008 |
| Navy | 17 | at | Delaware State | 5 | FINAL | Box Score | Recap | 600th career win for Navy's Paul Kostacopoulos |
| 4/29/2008 |
| Wofford | 5 | at | North Carolina A&T | 1 | FINAL | Box Score | Recap | |
| Missouri Valley Conference |
| 4/29/2008 |
| Kansas State | 3 | at | #11 Wichita State | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Illinois State | 7 | at | Illinois Wesleyan | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Murray State | 5 | at | Evansville | 6 | FINAL | Box Score | Recap | 11 innings |
| 4/29/2008 |
| Southern Illinois | 3 | at | Illinois | 2 | FINAL | Box Score | Recap | 11 innings |
| 4/29/2008 |
| Valparaiso | 3 | at | Bradley | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/29/2008 |
| Valparaiso | 1 | at | Bradley | 2 | FINAL | Box Score | Recap | 7 innings |
| Mountain West Conference |
| 4/29/2008 |
| #6 Texas A&M | 3 | at | Texas Christian | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| San Diego State | 2 | at | #20 Arizona | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Brigham Young | 17 | at | Northern Colorado | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Colorado Christian | 4 | at | Air Force | 13 | FINAL | Box Score | Recap | makeup of 4/16 game |
| 4/29/2008 |
| Nevada-Las Vegas | 1 | at | Cal State Northridge | 2 | FINAL | Box Score | Recap | |
| Northeast Conference |
| 4/29/2008 |
| Mount St. Mary's | 1 | at | #27 Virginia | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Quinnipiac |
| at | Boston College |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Sacred Heart |
| at | Fairfield |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Wagner | 2 | at | Lafayette | 9 | FINAL | Box Score | Recap | |
| Ohio Valley Conference |
| 4/29/2008 |
| Alabama | 10 | at | Samford | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Belmont | 5 | at | Tennessee-Martin | 6 | FINAL | Box Score | Recap | 7 innings |
| 4/29/2008 |
| Belmont | 14 | at | Tennessee-Martin | 5 | FINAL | Box Score | Recap | 7 innings |
| 4/29/2008 |
| Miami, Ohio | 7 | at | Eastern Kentucky | 9 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Morehead State | 0 | at | Louisville | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Murray State | 5 | at | Evansville | 6 | FINAL | Box Score | Recap | 11 innings |
| Pac 10 Conference |
| 4/29/2008 |
| San Diego State | 2 | at | #20 Arizona | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #25 Oregon State | 6 | at | Gonzaga | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Southern California | 4 | at | Cal Poly | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| UCLA | 2 | at | Pepperdine | 6 | FINAL | Box Score | Recap | |
| Patriot League |
| 4/29/2008 |
| Holy Cross |
| at | Rhode Island |
| Canceled | | Recap | CCD, inclement weather |
| 4/29/2008 |
| Navy | 17 | at | Delaware State | 5 | FINAL | Box Score | Recap | 600th career win for Navy's Paul Kostacopoulos |
| 4/29/2008 |
| Wagner | 2 | at | Lafayette | 9 | FINAL | Box Score | Recap | |
| Southeastern Conference |
| 4/29/2008 |
| Alabama | 10 | at | Samford | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Florida Gulf Coast |
| at | Florida |
| Postponed | | Recap | PPD, scheduling conflict |
| 4/29/2008 |
| Louisiana-Lafayette | 3 | at | Louisiana State | 5 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Mississippi | 10 | at | Memphis | 1 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Troy | 6 | at | Auburn | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Western Carolina | 5 | at | Tennessee | 2 | FINAL | Box Score | Recap | |
| Southern Conference |
| 4/29/2008 |
| Wake Forest | 11 | at | North Carolina-Greensboro | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Western Carolina | 5 | at | Tennessee | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Wofford | 5 | at | North Carolina A&T | 1 | FINAL | Box Score | Recap | |
| Southland Conference |
| 4/29/2008 |
| Texas State | 0 | at | #26 Texas | 11 | FINAL | Box Score | Recap | No-hitter for UT's Kenn Kasparek |
| 4/29/2008 |
| Baylor | 14 | at | Texas-Arlington | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Dallas Baptist | 8 | at | Sam Houston State | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Houston | 3 | at | Lamar | 2 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Houston Baptist | 3 | at | Texas A&M-Corpus Christi | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Nicholls State | 3 | at | Tulane | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Northwestern State | 13 | at | Louisiana-Monroe | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Texas-Pan American | 9 | at | Stephen F. Austin | 10 | FINAL | Box Score | Recap | |
| Southwestern Athletic Conference |
| 4/29/2008 |
| Alcorn State | 5 | at | Arkansas-Pine Bluff | 4 | FINAL | Box Score | | 7 innings |
| 4/29/2008 |
| Alcorn State | 13 | at | Arkansas-Pine Bluff | 12 | FINAL | Box Score | | |
| 4/29/2008 |
| Louisiana Tech | 13 | at | Grambling State | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Mississippi Valley State | 0 | at | Notre Dame | 4 | FINAL | Box Score | Recap | |
| Summit League |
| 4/29/2008 |
| Western Illinois | 4 | at | #9 Nebraska | 6 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| North Dakota State | 2 | at | Concordia Moorhead | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Olivet | 2 | at | Oakland | 15 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| South Dakota State | 21 | at | Sioux Falls | 4 | FINAL | Box Score | Recap | makeup of 4/28 game |
| Sun Belt Conference |
| 4/29/2008 |
| New Orleans | 9 | at | #29 Southern Mississippi | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Louisiana-Lafayette | 3 | at | Louisiana State | 5 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Northwestern State | 13 | at | Louisiana-Monroe | 4 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Troy | 6 | at | Auburn | 3 | FINAL | Box Score | Recap | |
| West Coast Conference |
| 4/29/2008 |
| Loyola Marymount | 11 | at | #7 UC Irvine | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #8 San Diego | 3 | at | #19 Cal State Fullerton | 12 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| #25 Oregon State | 6 | at | Gonzaga | 11 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Cal State Sacramento | 6 | at | Santa Clara | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| San Francisco | 6 | at | Pacific | 10 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| St. Mary's | 10 | at | Sonoma State | 3 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| UCLA | 2 | at | Pepperdine | 6 | FINAL | Box Score | Recap | |
| Western Athletic Conference |
| 4/29/2008 |
| Cal State Sacramento | 6 | at | Santa Clara | 7 | FINAL | Box Score | Recap | |
| 4/29/2008 |
| Louisiana Tech | 13 | at | Grambling State | 3 | FINAL | Box Score | Recap | |