| Game Date | Conference | Road Team | Score |
| Home Team | Score | Status | Box Score | Recap | Commentary |
|---|
| National Collegiate Baseball Writers Poll |
|---|
| 5/15/2008 | * | #2 North Carolina | 2 | at | #1 Miami, Florida | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #23 North Carolina State | 12 | at | #3 Florida State | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #5 Rice | 6 | at | Tulane | 0 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| San Diego State | 3 | at | #11 Cal State Fullerton | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Alabama |
| at | #12 Georgia |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 | * | #13 Vanderbilt | 6 | at | Florida | 8 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Bradley | 0 | at | #18 Wichita State | 10 | FINAL | Box Score | Recap | 8 innings, run rule |
| 5/15/2008 | * | Tennessee | 13 | at | #19 South Carolina | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Mississippi | 4 | at | #20 Kentucky | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Northwestern | 4 | at | #22 Michigan | 9 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #24 Louisiana State | 6 | at | Auburn | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Old Dominion | 2 | at | #26 North Carolina-Wilmington | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #27 Southern Mississippi |
| at | Alabama-Birmingham |
| Postponed |
| Recap | PPD to 5/16, field conditions |
| 5/15/2008 | * | #29 Georgia Tech | 2 | at | Virginia | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #30 East Carolina | 8 | at | Memphis | 1 | FINAL | Box Score | Recap |
|
| America East Conference |
|---|
| 5/15/2008 | * | Maine | 4 | at | Binghamton | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Stony Brook | 5 | at | Albany | 6 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Vermont | 0 | at | Hartford | 2 | FINAL | Box Score | Recap |
|
| Atlantic 10 Conference |
|---|
| 5/15/2008 | * | Rhode Island |
| at | North Carolina-Charlotte |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 | * | St. Bonaventure | 7 | at | Richmond | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | St. Joseph's | 6 | at | LaSalle | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Temple |
| at | St. Louis |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 | * | Duquesne | 3 | at | Dayton | 1 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Fordham | 10 | at | Massachusetts | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | George Washington |
| at | Xavier |
| Postponed |
| Recap | PPD to 5/16, rain |
| Atlantic Coast Conference |
|---|
| 5/15/2008 | * | Wake Forest | 10 | at | Boston College | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #2 North Carolina | 2 | at | #1 Miami, Florida | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #23 North Carolina State | 12 | at | #3 Florida State | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #29 Georgia Tech | 2 | at | Virginia | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Duke | 4 | at | Virginia Tech | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| Clemson | 9 | at | UCF | 1 | FINAL | Box Score | Recap |
|
| Atlantic Sun Conference |
|---|
| 5/15/2008 | * | Lipscomb | 8 | at | Campbell | 11 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | North Florida | 9 | at | Gardner-Webb | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Stetson | 6 | at | East Tennessee State | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Belmont | 6 | at | Mercer | 8 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Florida Gulf Coast | 1 | at | South Carolina-Upstate | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Kennesaw State | 7 | at | Jacksonville | 1 | FINAL | Box Score | Recap |
|
| Big 10 Conference |
|---|
| 5/15/2008 | * | Ohio State | 3 | at | Iowa | 4 | FINAL | Box Score | Recap | 10 innings |
| 5/15/2008 | * | Penn State | 7 | at | Minnesota | 11 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Purdue |
| at | Illinois |
| Postponed |
| Recap | PPD to 5/17, rain |
| 5/15/2008 | * | Northwestern | 4 | at | #22 Michigan | 9 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Indiana | 9 | at | Michigan State | 2 | FINAL | Box Score | Recap |
|
| Big East Conference |
|---|
| 5/15/2008 | * | Notre Dame | 4 | at | South Florida | 5 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Rutgers |
| at | Louisville |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 | * | Seton Hall | 18 | at | Georgetown | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | St. John's | 16 | at | Villanova | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | West Virginia |
| at | Cincinnati |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 | * | Connecticut | 14 | at | Pittsburgh | 10 | FINAL | Box Score | Recap |
|
| Big West Conference |
|---|
| 5/15/2008 |
| San Diego State | 3 | at | #11 Cal State Fullerton | 4 | FINAL | Box Score | Recap |
|
| Colonial Athletic Association |
|---|
| 5/15/2008 | * | William and Mary | 6 | at | George Mason | 8 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | William and Mary | 2 | at | George Mason | 7 | FINAL | Box Score | Recap | 7 innings (moved from 5/17, impending weather) |
| 5/15/2008 | * | Old Dominion | 2 | at | #26 North Carolina-Wilmington | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Delaware | 5 | at | Virginia Commonwealth | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Georgia State | 10 | at | Towson | 6 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | James Madison | 2 | at | Northeastern | 10 | FINAL | Box Score | Recap |
|
| Conference USA |
|---|
| 5/15/2008 | * | Marshall | 2 | at | Houston | 6 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #5 Rice | 6 | at | Tulane | 0 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #27 Southern Mississippi |
| at | Alabama-Birmingham |
| Postponed |
| Recap | PPD to 5/16, field conditions |
| 5/15/2008 | * | #30 East Carolina | 8 | at | Memphis | 1 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| Clemson | 9 | at | UCF | 1 | FINAL | Box Score | Recap |
|
| Division I Independents |
|---|
| 5/15/2008 |
| Dallas Baptist | 4 | at | San Francisco | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| LeMoyne | 3 | at | Iona | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| LeMoyne | 12 | at | Iona | 3 | FINAL | Box Score | Recap | 7 innings |
| 5/15/2008 |
| Northern Colorado | 17 | at | New York Tech | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| Presbyterian | 2 | at | The Citadel | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| Utah Valley State | 5 | at | Hawaii | 1 | FINAL | Box Score | Recap |
|
| Horizon League |
|---|
| 5/15/2008 | * | Youngstown State | 8 | at | Wisconsin-Milwaukee | 6 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Youngstown State | 5 | at | Wisconsin-Milwaukee | 4 | FINAL | Box Score | Recap | 13 innings |
| Metro Atlantic Athletic Conference |
|---|
| 5/15/2008 | * | Manhattan | 10 | at | Fairfield | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Manhattan | 8 | at | Fairfield | 2 | FINAL | Box Score | Recap | 7 innings |
| 5/15/2008 | * | Siena | 2 | at | Marist | 1 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Siena | 10 | at | Marist | 1 | FINAL | Box Score | Recap | 7 innings |
| 5/15/2008 | * | Canisius | 2 | at | Niagara | 3 | FINAL | Box Score | Recap | 12 innings |
| 5/15/2008 | * | Canisius | 2 | at | Niagara | 1 | FINAL | Box Score | Recap | 7 innings |
| 5/15/2008 |
| LeMoyne | 3 | at | Iona | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| LeMoyne | 12 | at | Iona | 3 | FINAL | Box Score | Recap | 7 innings |
| Mid American Conference |
|---|
| 5/15/2008 | * | Ohio | 6 | at | Buffalo | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Western Michigan | 11 | at | Northern Illinois | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Ball State | 5 | at | Toledo | 6 | FINAL | Box Score | Recap | 11 innings |
| 5/15/2008 | * | Bowling Green State | 15 | at | Akron | 9 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Eastern Michigan | 6 | at | Central Michigan | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Kent State |
| at | Miami, Ohio |
| Postponed |
| Recap | PPD to 5/16, inclement weather |
| Mid-Eastern Athletic Conference |
|---|
| 5/15/2008 | MEAC-03 | Delaware State | 6 | vs | Florida A&M | 7 | FINAL | Box Score | Recap | MEAC Tournament, Game 3 (Norfolk, VA) |
| 5/15/2008 | MEAC-02 | Norfolk State | 2 | vs | North Carolina A&T | 4 | FINAL | Box Score | Recap | MEAC Tournament, Game 2 (Norfolk, VA) |
| 5/15/2008 | MEAC-01 | Maryland-Eastern Shore | 1 | vs | Bethune-Cookman | 13 | FINAL | Box Score | Recap | 7 innings; MEAC Tournament, Game 1 (Norfolk, VA) |
| Missouri Valley Conference |
|---|
| 5/15/2008 | * | Missouri State | 12 | at | Northern Iowa | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Bradley | 0 | at | #18 Wichita State | 10 | FINAL | Box Score | Recap | 8 innings, run rule |
| 5/15/2008 | * | Evansville |
| at | Southern Illinois |
| Postponed |
| Recap | PPD to 5/16, inclement weather |
| 5/15/2008 | * | Illinois State |
| at | Indiana State |
| Postponed |
| Recap | PPD to 5/16, inclement weather |
| 5/15/2008 |
| Louisiana-Monroe | 5 | at | Creighton | 8 | FINAL | Box Score | Recap |
|
| Mountain West Conference |
|---|
| 5/15/2008 | * | Nevada-Las Vegas | 1 | at | Air Force | 10 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Texas Christian |
| at | New Mexico |
| Postponed |
| Recap | PPD to 5/16, inclement weather |
| 5/15/2008 |
| San Diego State | 3 | at | #11 Cal State Fullerton | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Brigham Young | 3 | at | Utah | 5 | FINAL | Box Score | Recap |
|
| Northeast Conference |
|---|
| 5/15/2008 | * | Mount St. Mary's | 6 | at | Quinnipiac | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Mount St. Mary's | 1 | at | Quinnipiac | 0 | FINAL | Box Score | Recap | 8 innings (moved from 5/17, impending weather) |
| Southeastern Conference |
|---|
| 5/15/2008 | * | Alabama |
| at | #12 Georgia |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 | * | #13 Vanderbilt | 6 | at | Florida | 8 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Tennessee | 13 | at | #19 South Carolina | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Mississippi | 4 | at | #20 Kentucky | 12 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | #24 Louisiana State | 6 | at | Auburn | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Arkansas | 5 | at | Mississippi State | 6 | FINAL | Box Score | Recap |
|
| Southern Conference |
|---|
| 5/15/2008 | * | College of Charleston |
| at | Western Carolina |
| Postponed |
| Recap | PPD to 5/16, inclement weather |
| 5/15/2008 | * | Davidson | 1 | at | North Carolina-Greensboro | 9 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Georgia Southern |
| at | Furman |
| Postponed |
| Recap | PPD to 5/16, rain |
| 5/15/2008 |
| Presbyterian | 2 | at | The Citadel | 3 | FINAL | Box Score | Recap |
|
| Southland Conference |
|---|
| 5/15/2008 | * | Lamar | 5 | at | McNeese State | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Northwestern State | 3 | at | Central Arkansas | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Southeastern Louisiana | 15 | at | Nicholls State | 1 | FINAL | Box Score | Recap | 7 innings, run rule |
| 5/15/2008 | * | Stephen F. Austin | 4 | at | Sam Houston State | 10 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Texas A&M-Corpus Christi | 5 | at | Texas-Arlington | 6 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Texas State | 10 | at | Texas-San Antonio | 3 | FINAL | Box Score | Recap |
|
| Southwestern Athletic Conference |
|---|
| 5/15/2008 | SWAC-04 | Alabama State | 4 | vs | Southern | 14 | FINAL | Box Score |
| 7 innings; SWAC Tournament, Game 4 (Baton Rouge, LA) |
| 5/15/2008 | SWAC-03 | Texas Southern | 10 | vs | Jackson State | 9 | FINAL | Box Score | Recap | SWAC Tournament, Game 3 (Baton Rouge, LA) |
| 5/15/2008 | SWAC-02 | Prairie View A&M | 15 | vs | Alcorn State | 5 | FINAL | Box Score |
| 7 innings; SWAC Tournament, Game 2 (Baton Rouge, LA) |
| Summit League |
|---|
| 5/15/2008 | * | Oral Roberts | 3 | at | IUPU-Fort Wayne | 2 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | South Dakota State | 4 | at | North Dakota State | 5 | FINAL | Box Score | Recap | 10 innings |
| 5/15/2008 | * | Southern Utah | 6 | at | Oakland | 1 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Western Illinois | 0 | at | Centenary | 8 | FINAL | Box Score | Recap |
|
| Sun Belt Conference |
|---|
| 5/15/2008 | * | Middle Tennessee State | 7 | at | Western Kentucky | 5 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | New Orleans | 2 | at | Louisiana-Lafayette | 4 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | South Alabama | 7 | at | Troy | 0 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Arkansas-Little Rock | 3 | at | Arkansas State | 1 | FINAL | Box Score | Recap |
|
| 5/15/2008 | * | Florida Atlantic | 10 | at | Florida International | 3 | FINAL | Box Score | Recap |
|
| 5/15/2008 |
| Louisiana-Monroe | 5 | at | Creighton | 8 | FINAL | Box Score | Recap |
|
| West Coast Conference |
|---|
| 5/15/2008 |
| Dallas Baptist | 4 | at | San Francisco | 2 | FINAL | Box Score | Recap |
|
| Western Athletic Conference |
|---|
| 5/15/2008 |
| Utah Valley State | 5 | at | Hawaii | 1 | FINAL | Box Score | Recap |
|